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This meeting was sponsored by the National Institute of Allergy and Infectious Diseases and was held Tuesday, June 16 – Wednesday, June 17, 2015 in Rockville, Maryland.

The objective of this international meeting was to convene basic and clinical researchers, as well as mathematical modellers, pharmacometricians, representatives from other funding organizations, and representatives of pertinent US Federal Agencies (CDC, FDA, NIH) to discuss what pharmacologic, microbiologic, and other factors can be combined to arrive at approaches for evaluating new phasing schedules for existing drugs and drugs in development to maximize their impact in the shortest possible overall treatment regimen. Discussions bore on state-of-the-art methods to measure and improve outcome while reducing drug exposure and to characterize and manage drug-related toxicities. Clinical testing of optimized TB drug combinations in field conditions using innovative trial and surveillance strategies were also discussed.

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