5 Monivong Boulevard, P.O Box. 983, Phnom Penh, Cambodia accueil@pasteur-kh.org

Institut Pasteur du Cambodge has developed technologies for the diagnosis of infectious diseases, incorporating special care in the standardization of techniques through ongoing external quality controls.

This know-how is based on qualified employees and efficient infrastructure. The modern equipment installed in modern and secure laboratories ensures the best quality of analysis and their results. This professional environment applies to Biomedical Analysis as well as research activities on the study of micro-organisms pathogenic to humans: bacteria (tuberculosis, cholera, melioidosis, enteropathogenic bacteria, leptospirosis …), fungi (candidiasis, aspergillosis, cryptococcosis …), viruses (HIV, influenza, respiratory viruses, dengue, Japanese encephalitis, Chikungunya, EV71 and other enteroviruses, hantavirus, rabies …), parasites (malaria …).

Infrastructures

The Institut Pasteur du Cambodge owns five laboratories type P2 and 2 laboratories P2 + necessary for handling hazardous microorganisms but not fatal for humans or for which vaccines and treatments exists: tuberculosis, rabies, respiratory viruses classics etc.. Laboratories are placed in depression zone and entrance is through an airlock. Pathogens are handled in vertical laminar flow hoods to protect the operator.

IPC has largely improved its equipments for research and public health programs, thanks to grant supports with collaborative institutions and the support of Institut Pasteur in Paris.

  1. IPC uses the BSL-3 laboratory for service and research purposes (four modules occupied for MDR- and XDR-TB, H5N1 Avian flu, new or unknown viruses isolated from severe human cases, and one ASL-3 animal facility for research projects on virus transmission and pathophysiology experiments. There are very few such laboratories in Southeast Asia.
    BSL3   P3
  2. A renewed Immunology Platform provides expertise on cellular immune responses to infections, with emphasis on NK cell activation during HIV, HIV/TB, and dengue infections. The platform is equipped with FACScalibur and F500 flow cytometer.
    PHP_2530
  3. IPC has renovated and expanded its animal facility and has built up an insectary in 2011.
    animal_facility
  4. The capacity of molecular biology has been recently improved with new equipments:  GeneXpert for TB, LAMP for malaria and TB; Luminex, 454 High-throughput sequencing.
  5. The Malaria Molecular Epidemiology Unit has acquired a mobile laboratory for on-site blood sample analysis in remote areas of Cambodia.
    lab-mobile
  6. A regional platform (PR-Asia) for research on transmissible infection and emerging pathogens (founded by INSERM, ANRS, IRD, Fondation Mérieux and Institut Pasteur) build up in 2013 to provide laboratories for researchers working on transversal projects with IPC.
    pr-asia

The quality of medical analysis and biomedical research programs are based on a variety of high-tech equipment to study biological, microbiological, genetic and pathophysiological infectious diseases, and on staff with a good knowledge on the pathogens studied. Infrastructure and safety of this technology platform are controlled by an engineer on hygiene, safety, quality and metrology. Maintenance of the platform is provided by technicians and engineers specializing in laboratory equipment (platform itself is under continuous maintenance by companies) and used by competent researchers and trained professionals. The technical platform is open to other organizations for training and research programs in collaboration with our teams.