Deadline: September 30^th, 2023

The Institut Pasteur du Cambodge (IPC) is a Cambodian non-for-profit research institution established in 1953, IPC is today a scientific research establishment declared of public utility placed under the high patronage of the Ministry of Health of the Kingdom of Cambodia and under the responsibility of the Institute Pasteur on the scientific and technical levels. The IPC is a member of the Pasteur Network, which brings together 33 institutes present on five continents. It shares the Pasteurian values and the ethical charter to which the Pasteur Institutes are bound. The IPC has more than 250 employees, including about 30 expatriates of 10 nationalities and includes 5 research units. It carries out research activities in health biology, public health and service activities (Medical Biology Laboratory, vaccinations and water and food analyses) and training.

The Immunology Unit at Institut Pasteur du Cambodge seeks a motivated postdoctoral scientist to study adaptive immune responses to Plasmodium vivax in the framework of an NIH funded project. This project aims at understanding the host immune characteristics that are associated with protection from clinical Plasmodium vivax malaria. Our objectives are to elucidate the mechanisms driving the development of broadly inhibiting anti-Plasmodium vivax antibodies and to uncover immune pathways of protection. Accomplishment of these goals will be reached by leveraging a longitudinal Plasmodium vivax patient cohort displaying contrasted clinical outcome of infection, in combination with state-of-the art technologies on site and our ability to perform short-term cultures of Plasmodium vivax. The successful candidate will be part of a team of 8-10 international researchers and will participate in an international research project in a stimulating environment.

The lnstitut Pasteur du Cambodge (IPC) is recruiting a full-time postdoctoral scientist in the Immunology Unit for a 24 months contract.

RECRUITMENT CONDITIONS

• PhD degree in Immunology or closely related field
• Language required: English
• Start date flexible
• Full time position for minimum of 2 years
• Salary will be covered by the lab and will depend on the expertise of the candidate and includes an expatriate package

MAIN RESPONSIBILITIES

• The project aims to understand B and T cell response to Plasmodium vivax malaria in humans with different disease outcomes after infection in an NIH-funded project
• Manage a research project
• Supervise PhD students and M2 students
• Work independently

QUALIFICATIONS

• Expertise in human Immunology required
• Expertise in human B and T cell biology is an asset
• Expertise in host-pathogen (plasmodium) interaction is an asset

Immunology laboratory is located at Institut Pasteur du Cambodge in Phnom Penh, and offers up-to-date infrastructures (FACSAria Fusion, single cell analysis platform, sequencing platform, BSL3 laboratory). The lab is part of the Institut Pasteur International Network and Centers of Research on Emerging Infectious Diseases Network (NIH).

Publications from the lab related to the topic: Guerrero D et al, Nat Commun 2022, Bournazos et al, Science 2021; Popovici et al, Nat Commun 2021; More information can be found on https://www.pasteur-kh.org/immunology and https://www.pasteur-kh.org/malaria

Please send your application via email with your CV including contact details of two references to Tineke Cantaert ([email protected]) before September 30^th, 2023.