Close
The Institut Pasteur du Cambodge remains a bridgehead of Pasteur-inspired research on infectious diseases in Cambodia. The Institute, a very active member of the Institut Pasteur International Network (IPIN), is a government-approved non-profit research institution. The Institute was created in 1953 and reopened in 1992 after the signature of an agreement with the Royal Government of Cambodia (RGC), which was renewed by an endorsement in 2013. The Institute is under the senior oversight of the Cambodian Ministry of Health (MoH), on behalf of which it carries out high excellence life sciences and health research, public health and health services as well as training and education activities. The Institute has reinforced this mission over the past 25 years in collaboration with national and international institutions. It contributes to the diagnosis, research, and prevention of the priority infectious diseases and emerging pathogens in Cambo dia and the Greater Mekong Sub-region. It plays a major role in microbiological monitoring and research in cooperation with national and international partners, as well as several IPIN Institutes, first and foremost the Institut Pasteur in Paris…
Antibody fucosylation predicts disease severity in secondary dengue infection. Stylianos Bournazos, Hoa Thi My Vo, Veasna Duong, Heidi Auerswald, Sowath Ly, Anavaj Sakuntabhai, Philippe Dussart, Tineke Cantaert, Jeffrey V. Ravetch, Science, 04 Jun 2021
Direct Infection of B Cells by Dengue Virus Modulates B Cell Responses in a Cambodian Pediatric Cohort. Vinit Upasani, Hoa Thi My Vo, Heidi Auerswald, Denis Laurent, Sothy Heng, Veasna Duong, Izabela A. Rodenhuis-Zybert, Philippe Dussart, and Tineke Cantaert, Frontiers in Immunology, 12 Feb 2021
Malaria in Cambodia: A Retrospective Analysis of a Changing Epidemiology 2006-2019. Srean Chhim , Patrice Piola, Tambri Housen, Vincent Herbreteau, Bunkea Tol, International Journal of Environmental Research and Public Health, 18 Feb 2021
Recent and massive invasion of Aedes (Stegomyia) albopictus (Skuse, 1894) in Phnom Penh, Cambodia. P O Maquart, D Fontenille, S Boyer, Parasites & Vectors, 18 Feb 2021
Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters. Jean Popovici, Kieran Tebben, Benoit Witkowski, David Serre, International Journal for Parasitology: Drugs and Drug, Resistance 24 Jan 2021
Choosing interventions to eliminate forest malaria: preliminary results of two operational research studies inside Cambodian forests. Amber Kunkel, Chea Nguon, Sophea Iv, Srean Chhim, Dom Peov, Phanith Kong, Saorin Kim, Sarun Im, Mark Debackere, Nimol Khim, Jean Popovici, Sreynet Srun, Amélie Vantaux, Jean-Olivier Guintran, Benoit Witkowski, Patrice Piola, Malaria Journal, 20 Jan 2021
Assessment of inactivation procedures for SARS-CoV-2. Heidi Auerswald, Sokhoun Yann, Sokha Dul 2 , Saraden In, Philippe Dussart, Nicholas J Martin, Erik A Karlsson, Jose A Garcia-Rivera, The Journal of General Virology, 08 Jan 2021
Autoantibody Profiling in Plasma of Dengue Virus-Infected Individuals. Hoa Thi My Vo, Veasna Duong, Sowath Ly, Quan-Zhen Li, Philippe Dussart, Tineke Cantaert, Pathogens, 18 Dec 2020
Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue. Vinit Upasani, Carolina Scagnolari, Federica Frasca , Nikaïa Smith, Vincent Bondet, Axelle Vanderlinden, Sokchea Lay, Heidi Auerswald, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Guido Antonelli, Philippe Dussart , Darragh Duffy, Tineke Cantaert, Frontiers in Immunology, 17 Dec 2020
Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses. Paul F Horwood, Thomas Fabrizio, Srey Viseth Horm, Artem Metlin, Sopheaktra Ros, Songha Tok, Trushar Jeevan, Patrick Seiler, Phalla Y, Sareth Rith, Annika Suttie, Philippe Buchy, Erik A Karlsson, Richard Webby, Philippe Dussart, Emerging Microbes & Infections, 09 Dec 2020
Epidemiology and pathological progression of erythematous lip lesions in captive sun bears (Helarctos malayanus).Kirsty Officer, Mathieu Pruvot, Paul Horwood, Daniela Denk, Kris Warren, Vibol Hul, Nhim Thy, Nev Broadis, Philippe Dussart, Bethany Jackson, PloS One, 01 Dec 2020
Dengue viremia kinetics in asymptomatic and symptomatic infection. Ponpan Matangkasombut, Kajohnpong Manopwisedjaroen. Nada Pitabut, Sasikanya Thaloengsok, Swangjit Suraamornkul, Tawatchai Yingtaweesak, Veasna Duong, Anavaj Sakuntabhai, Richard Paul, Pratap Singhasivanon, International Journal of Infectious Diseases, 01 Dec 2020
Patterns of foraging activity and fidelity in a southeast Asian flying fox. Elodie Schloesing, Rémi Chambon, Annelise Tran, Kinley Choden, Sébastien Ravon, Jonathan H. Epstein, Thavry Hoem, Neil Furey, Morgane Labadie, Mathieu Bourgarel, Hélène M. De Nys, Alexandre Caron, and Julien Cappelle, Movement Ecology, 10 Nov 2020
Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests. Sandra Incardona, David Bell, Ana Campillo, Jane Cunningham, Frederic Ariey, Thierry Fandeur, Jennifer Luchavez, Christian Anthony Luna, Didier Ménard, Sina Nhem, Johanna Beulah Sornillo, Benoit Witkowski, Zachary Katz, Sabine Dittrich, Xavier C Ding, Malaria Journal, 13 Jul 2020
Whole genome sequencing and phylogenetic characterization of a novel bat-associated picornavirus-like virus with an unusual genome organization. Sarah Temmam , Vibol Hul, Thomas Bigot, Maël Bessaud, Delphine Chrétien, Thavry Hoem, Christopher Gorman, Veasna Duong, Philippe Dussart, Julien Cappelle, Marc Eloit, Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, February 2020.
Autoantibody Profiling in Plasma of Dengue Virus-Infected Individuals. Hoa Thi My Vo, Veasna Duong, Sowath Ly, Quan-Zhen Li, Philippe Dussart, Tineke Cantaert, Pathogens, 18 Dec 2020
Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue. Vinit Upasani, Carolina Scagnolari, Federica Frasca , Nikaïa Smith, Vincent Bondet, Axelle Vanderlinden, Sokchea Lay, Heidi Auerswald, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Guido Antonelli, Philippe Dussart , Darragh Duffy, Tineke Cantaert, Frontiers in Immunology, 17 Dec 2020
Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses. Paul F Horwood, Thomas Fabrizio, Srey Viseth Horm, Artem Metlin, Sopheaktra Ros, Songha Tok, Trushar Jeevan, Patrick Seiler, Phalla Y, Sareth Rith, Annika Suttie, Philippe Buchy, Erik A Karlsson, Richard Webby, Philippe Dussart, Emerging Microbes & Infections, 09 Dec 2020
Epidemiology and pathological progression of erythematous lip lesions in captive sun bears (Helarctos malayanus).Kirsty Officer, Mathieu Pruvot, Paul Horwood, Daniela Denk, Kris Warren, Vibol Hul, Nhim Thy, Nev Broadis, Philippe Dussart, Bethany Jackson, PloS One, 01 Dec 2020
Dengue viremia kinetics in asymptomatic and symptomatic infection. Ponpan Matangkasombut, Kajohnpong Manopwisedjaroen. Nada Pitabut, Sasikanya Thaloengsok, Swangjit Suraamornkul, Tawatchai Yingtaweesak, Veasna Duong, Anavaj Sakuntabhai, Richard Paul, Pratap Singhasivanon, International Journal of Infectious Diseases, 01 Dec 2020
Comparison of Japanese Encephalitis Force of Infection in Pigs, Poultry and Dogs in Cambodian Villages, 2020 Sep 1Heidi Auerswald, Saraden In, Philippe Dussart, Véronique Chevalier, Veasna Duong, Héléna Ladreyt, Sothyra Tum, Sreymom Ken, Leangyi Heng, Sokchea Lay, Chakriyouth Top, Sowath Ly, Benoit Durand
TLR2 on blood monocytes senses dengue virusinfection and its expression correlates with diseasepathogenesis : Nature Communication, 25Jun2020. José A. Aguilar-Briseño/ Vinit Upasani/ Bram M. ter Ellen/ Jill Moser/ Mindaugas Pauzuolis/Mariana Ruiz-Silva/ Sothy Heng/ Denis Laurent/, Rithy Choeung/ Philippe Dussart/ Tineke Cantaert/Jolanda M. Smit& Izabela A. Rodenhuis-Zybert
Improved detection of dengue and Zika viruses using multiplex RT-qPCR assays : J Virol Methods, 2020May14.Ou TP / Yun C / Auerswald H / In S / Leang R / Huy R / Chhoeung R / Dussart P / Duong V.
Novel genome sequences of cell-fusing agent virus allow comparison of virus phylogeny with the genetic structure of Aedes aegypti populations : Virus Evol, 2020Apr29 Baidaliuk A / Lequime S / Moltini-Conclois I / Dabo S / Dickson LB / Prot M / Duong V / Dussart P / Boyer S / Shi C / Matthijnssens J / Guglielmini J / Gloria-Soria A / Simon-Lorière E / Lambrechts L.
Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy : Cancers (Basel),2020Apr18. Kretschmer M / Kadlubowska P / Hoffmann D / Schwalbe B / Auerswald H / Schreiber M
Serological Evidence for Japanese Encephalitis and West Nile Virus Infections in Domestic Birds in Cambodia : Frontiers in veterinary science,2020Jan29. Auerswald H / Ruget AS / Ladreyt H / In S / Mao S / Sorn S / Tum S / Duong V / Dussart P / Cappelle J / Chevalier V.
Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests. Sandra Incardona, David Bell, Ana Campillo, Jane Cunningham, Frederic Ariey, Thierry Fandeur, Jennifer Luchavez, Christian Anthony Luna, Didier Ménard, Sina Nhem, Johanna Beulah Sornillo, Benoit Witkowski, Zachary Katz, Sabine Dittrich, Xavier C Ding July 13th, 2020
Clinical and in Vitro Resistance of Plasmodium Falciparum to Artesunate-Amodiaquine in Cambodia : Clin Infect Dis,2020May27, Melissa Mairet-Khedim/ Rithea Leang/ Camille Marmai/ Nimol Khim/ Saorin Kim/ Sopheakvatey Ke/ Chhayleang Kauy/ Nimol Kloeung/ Rotha Eam/, Sophy Chy/ Brigitte Izac/ Denis Mey Bouth/ Maria Dorina Bustos/ Pascal Ringwald/ Frederic Ariey/ Benoit Witkowski
Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis : PLoS Med. 2020 May 14, Pfeffer DA / Ley B / Howes RE / Adu P / Alam MS / Bansil P / Boum Y 2nd / Brito M / Charoenkwan P / Clements A / Cui L / Deng Z / Egesie OJ / Espino FE /, von Fricken ME / Hamid MMA / He Y / Henriques G / Khan WA / Khim N / Kim S / Lacerda M / Lon C / Mekuria AH / Menard D / Monteiro W / Nosten F / Oo NN /, ^Pal S / Palasuwan D / Parikh S / Pitaloka Pasaribu A / Poespoprodjo JR / Price DJ / Roca-Feltrer A / Roh ME / Saunders DL / Spring MD / Sutanto I / Ley-Thriemer K /, Weppelmann TA / von Seidlein L / Satyagraha AW / Bancone G / Domingo GJ / Price RN.
Pyronaridine-artesunate Efficacy and Safety in Uncomplicated Plasmodium Falciparum Malaria in Areas of Artemisinin-resistant Falciparum in Viet Nam (2017-2018) : Clin Infect Dis ,2020May06, Quang Bui P / Hong Huynh Q / Thanh Tran D / Thanh Le D / Quang Nguyen T / Van Truong H / Khim N / Witkowski B / Cong Tran D / Bustos MD / Ringwald P / Thi Ta T.
Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia : J Antimicrob Chemother,2020 Mar24, Roesch C / Mairet-Khedim M / Kim S / Lek D / Popovici J / Witkowski B.
Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3 : Cell Chem Biol,2020Mar24, Posfai D / Maher SP / Roesch C / Vantaux A / Sylvester K / Péneau J / Popovici J / Kyle DE / Witkowski B / Derbyshire ER.
Autoantibody Profiling in Plasma of Dengue Virus-Infected Individuals. Hoa Thi My Vo, Veasna Duong, Sowath Ly, Quan-Zhen Li, Philippe Dussart, Tineke Cantaert. December 18th, 2020
Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue. Vinit Upasani, Carolina Scagnolari, Federica Frasca , Nikaïa Smith, Vincent Bondet, Axelle Vanderlinden, Sokchea Lay, Heidi Auerswald, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Guido Antonelli, Philippe Dussart , Darragh Duffy, Tineke Cantaert December 17th, 2020
TLR2 on blood monocytes senses dengue virusinfection and its expression correlates with diseasepathogenesis : Nature Communication, 25Jun2020, José A. Aguilar-Briseño/ Vinit Upasani/ Bram M. ter Ellen/ Jill Moser/ Mindaugas Pauzuolis/Mariana Ruiz-Silva/ Sothy Heng/ Denis Laurent/, Rithy Choeung/ Philippe Dussart/ Tineke Cantaert/Jolanda M. Smit& Izabela A. Rodenhuis-Zybert
A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection, Sébastien Boyer, Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W Sutherland, Jeffrey C Hertz, Jean-Marc Bonneville, Victor Arnaud, Camille Noûs, Bénédicte Fustec, Sébastien Marcombe, Jean-Philippe David
Strategic Approach, Advances, and Challenges in the Development and Application of the SIT for Area-Wide Control of Aedes albopictus Mosquitoes in Reunion Island, 2020 Nov 7, Sébastien Boyer, Didier Fontenille, Louis Clément Gouagna, David Damiens, Clélia F Oliva, Gilbert Le Goff, Cécile Brengues, Jean-Sébastien Dehecq, Jocelyn Raude, Frédéric Simard
Dynamics and diversity of mosquito vectors of Japanese encephalitis virus in Kandal province, Cambodia, September 1, 2020, Philippe Dussart, Sébastien Boyer, Borin Peng, Senglong Pang, Véronique Chevalier, Veasna Duong, Christopher Gorman, Didier Fontenille, Julien Cappelle
Current vector research challenges in the greater Mekong subregion for dengue, Malaria, and Other Vector-Borne Diseases: A report from a multisectoral workshop March 2019, July 30, 2020, Rekol Huy, Sebastien Boyer, Rebecca C. Christofferson, Bruce A. Wilcox, Daniel M. Parker, Hans J. Overgaard, Gregor Devine, Jeffrey Hii, Vu Sinh Nam, Kobporn Boonnak, Sazaly Abubakar, Stephen S. Whitehead, Leang Rithea, Tho Sochantha, Thomas E. Wellems, Jesus G. Valenzuela, Jessica E. Manning
High diversity of mosquito vectors in Cambodian primary schools and consequences for arbovirus transmission : Plos One,2020June05, Sebastien Boyer / Sebastien Marcombe / Sony Yean / Didier Fontenille
Two new phlebotomine sandflies (Diptera: Psychodidae) from the forest edge in Madagascar: the anthropophilic Phlebotomus artemievi sp. nov. and Sergentomyia maroantsetra ensis sp. nov : Parasitol Res,2020Apr03, Randrianambinintsoa FJ / Depaquit J / Martinet JP / Golden CD / Boyer S / Robert V / Tantely LM.
Ability of the Premise Condition Index to Identify Premises with Adult and Immature Aedes Mosquitoes in Kampong Cham, Cambodia : Am J Trop Med Hyg,2020Apr06. Hustedt J / Doum D / Keo V / Ly S / Sam B / Chan V / Boyer S / Liverani M / Alexander N / Bradley J / Prasetyo DB / Rachmat A / Lopes S / Leang R / Hii J.
GloPID-R Report on Chikungunya, O’Nyong-Nyong and Mayaro Virus, Part 5: Entomological Aspects : Antiviral Res,2020 Feb05. Pezzi L / Diallo M / Rosa-Freitas MG / Vega-Rua A / Ng LFP / Boyer S / Drexler JF / Vasilakis N / Lourenco-de-Oliveira R /, Weaver SC / Kohl A / de Lamballerie X / Failloux AB; GloPID-R chikungunya / o’nyong-nyong and Mayaro virus Working Group.
Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue. Vinit Upasani, Carolina Scagnolari, Federica Frasca , Nikaïa Smith, Vincent Bondet, Axelle Vanderlinden, Sokchea Lay, Heidi Auerswald, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Guido Antonelli, Philippe Dussart , Darragh Duffy, Tineke Cantaert December 17th, 2020
Comparison of Japanese Encephalitis Force of Infection in Pigs, Poultry and Dogs in Cambodian Villages, 2020 Sep 1, Heidi Auerswald, Saraden In, Philippe Dussart, Véronique Chevalier, Veasna Duong, Héléna Ladreyt, Sothyra Tum, Sreymom Ken, Leangyi Heng, Sokchea Lay, Chakriyouth Top, Sowath Ly, Benoit Durand
Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults, 2020JUNE18 (PDF FORMAT), Eugène Messou, François-Xavier Blanc, Anani D. Badje, Delphine Gabillard, Maryline Bonnet, Conrad Muzoora, Duc Bang Nguyen, Sovannarith Samreth, Laurence Borand, Anaïs Domergue, Delphine Rapoud, Naome Natukunda, Sopheak Thai, Serge P. Eholié, Sylvain Juchet, Serge K. Domoua, Stephen D. Lawn, Xavier Anglaret
Frequency, risk factors, and complications of induced abortion in ten districts of Madagascar: results from a cross-sectional household survey : BMC Womens Health,2020May06, Ratovoson R / Kunkel A / Rakotovao JP / Pourette D / Mattern C / Andriamiadana J / Harimanana A / Piola P.
HBeAg rapid test and alanine aminotransferase level-based algorithm to identify pregnant women at risk of HBV mother-to-child transmission: the ANRS 12345 TA PROHM study : Clin Infect Dis,2020Mar19, Segeral O / Dim B / Durier C / Prak S / Chhim K / Vong C / Pech S / Tiv S / Nem B / Hout K / Nouhin J / Chhun S / Borand L
Serological Evidence of West Nile and Usutu Viruses Circulation in Domestic and Wild Birds in Wetlands of Mali and Madagascar in 2008 : Int J Environ Res Public Health,2020Mar18, Chevalier V / Marsot M / Molia S / Rasamoelina H / Rakotondravao R / Pedrono M / Lowenski S / Durand B / Lecollinet S / Beck C.
Serological Evidence for Japanese Encephalitis and West Nile Virus Infections in Domestic Birds in Cambodia : Frontiers in veterinary science,2020Jan29, Auerswald H / Ruget AS / Ladreyt H / In S / Mao S / Sorn S / Tum S / Duong V / Dussart P / Cappelle J / Chevalier V.
Mortality Among People With HIV Treated for Tuberculosis Based on Positive, Negative, or No Bacteriologic Test Results for Tuberculosis: The IeDEA Consortium : Open Forum Infect Dis,2020Jan10
CTX-M-55-type ESBL-producing Salmonella enterica are emerging among retail meats in Phnom Penh, Cambodia : J Antimicrob Chemother,2018Oct30, Nadimpalli M / Fabre L / Yith V / Sem N / Gouali M / Delarocque-Astagneau E / Sreng N / Le Hello S; Members of the BIRDY study group
Co-circulation of Influenza A H5, H7, and H9 Viruses and Co-infected Poultry in Live Bird Markets, Cambodia : Emerging Infectious Diseases, 2018Feb08, Horwood PF / Horm SV / Suttie A / Thet S / Y P / Rith S / Sorn S / Holl D / Tum S / Ly S / Karlsson E / Tarantola A / Dussart P
Antibiotic susceptibility and molecular characterization of resistance genes among Escherichia coli and among Salmonella subsp. in chicken food chains : ScienceDirect, 2017Jul12, Yith V / Kruy SL / Heng S / Kerleguer A / Aidara-Kane A
