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Epidemiology and Public Health Unit

The Epidemiology and Public Health Unit of the Pasteur Institute of Cambodia conducts operational epidemiological research studies on major public health challenges in Cambodia. Specifically, the work carried out aims to improve the understanding of the transmission of infectious and emerging diseases and to improve the prevention, diagnosis and treatment of priority pathologies in the most vulnerable populations.


Epidemiology and Public Health Unit

For more information about this unit, please contact

Main Missions and Team Presentation

Our mission is to implement epidemiological and clinical research studies, based on a cross-sectional and multidisciplinary approach, and to make recommendations for interventions and health policies based on scientific knowledge and evidence. The purpose of the actions carried out within the unit is thus to understand and improve the health and well-being of populations and to reduce health inequalities.


Our research activities call upon different disciplines including epidemiology applied to infectious diseases and environmental health, clinical research, biostatistics, mathematical modeling, health geography as well as human and social sciences applied to health. It is most often based on the collection and analysis of data relating to population samples, more or less large depending on the objectives and designs of the various research projects.


The main research themes studied in recent years target specific public health problems in Cambodia and more broadly in Southeast Asia including rabies, arboviruses, HIV, Tuberculosis, Malaria, Nipah virus, Antibiotic resistance, Leptospirosis, Influenzae viruses, Sars-CoV-2, etc. .


In 2023, the unit, composed of 52 people, is organized around 5 specific and complementary groups including: 

  • The Community Epidemiology Group, led by Dr. Sowath Ly, who has extensive experience in community epidemiology research projects on rabies, dengue, avian influenza and investigations of epidemics and health alert situations; 
  • The Clinical Research Group, led by Dr. Nathalie de Rekeneire, which pilots clinical trials and contributes to guide international prevention, diagnosis and treatment strategies for vulnerable populations with HIV, tuberculosis, hepatitis and some vaccine preventable and emerging infectious diseases. 
  • The One Health group, led by Dr. Hélène Guis, which arises from the collaboration between CIRAD and IPC to tackle the human, animal and environmental components of disease transmission and prevention in a constructive and coordinated One Health approach. Its focus is on zoonotic and vector-borne diseases. 
  • The Geo Health group , coordinated by Dr. Vincent Herbreteau from the IRD, which is specialised in the study of the effects of the environment and geographical factors on human health, bringing a useful expertise for the research activities conducted within the unit.
  • The Methodology and Data Analysis group, coordinated by Dr. Claude Flamand, which aims to develop and implement methodological tools and approaches adapted to the studies carried out including study designs, data management and analysis resulting from the research work carried out; 

Main Field of Research

Improving Prevention, Diagnosis, and Treatment of Infectious Diseases in Vulnerable Populations


Despite significant progress, Cambodia continues to face serious challenges in detecting and preventing Tuberculosis (TB) cases, particularly among people living with HIV. Many challenges also remain in reducing the prevalence of HIV, TB, and exposure to viral hepatitis B or C in vulnerable populations. The lack of access to efficient, affordable, and easy-to-use diagnostic tools and late screening in certain exposed populations are still important challenges for health authorities to reduce the burden of morbidity and mortality. The clinical research group of the Epidemiology and Public Health Unit conducts important research activities aimed at improving access to diagnosis and systematic and rapid detection of HIV or TB in exposed populations. This work contributes to important multicenter randomized trials evaluating the impact and cost-effectiveness of new therapeutic approaches, the effectiveness of new molecules, or the performance of new diagnostic tools, providing.

Assessing Immunity after Rabies Post-Exposition Prophylaxis

International health authorities support a major effort to eliminate canine rabies in humans by 2030. While this goal could be achieved in the long term by mass vaccination of dogs, improving access to adequate and timely post-exposure prophylaxis could save lives in the short term. The Epidemiology and Public Health Unit conducts studies on the immune response induced by post-exposure prophylaxis to provide authorities with useful knowledge to optimize recommended vaccine regimens and improve compliance in exposed populations. This work improves the knowledge on the characteristics of protection, humoral and cell-mediated response related to vaccine regimens and contributes to the adaptation of the WHO recommendations for rabies post-exposure prophylaxis.

Investigating the Circulation of Zoonotic Pathogens in a One Health Perspective


One Health (OH) is an integrated multisectorial and multidisciplinary approach that recognizes the close links and interdependence of human, domestic and wild animal, plant, and environmental health. OH approaches are key to better understand, prevent, and control zoonotic pathogens. In Cambodia, 80% of the population lives in rural areas, and most households own animals (poultry, swine, cattle, dogs), with common contacts with wildlife (consumption, tourism…). The Epidemiology and Public Health Unit develops cross-sectional or longitudinal surveys in which the health of humans is monitored alongside the health of domestic or wild animals to identify reservoirs, evaluate prevalence and incidence of zoonotic pathogens in the different hosts in space and time. The aims of these approaches are to better understand where, when, how transmission takes place (frequency, duration, location, circumstances, types of contacts), the role of animals (reservoirs or sentinels) in pathogen circulation, which prevention or control strategies are deployed or could be deployed and their efficacy, and how to strengthen One Health surveillance.

Implementing Population-Based Surveys to Study Human Exposure and Transmission Dynamics of Priority Infectious Diseases


Despite the growing impact of infectious diseases worldwide and the strengthening of surveillance systems, many gaps remain in our understanding of the mechanisms of transmission and maintenance of causative pathogens in exposed areas. Traditional epidemiological surveillance only provides information on symptomatic cases, leaving asymptomatic or medically unattended infections and the immune landscape at the population level unaccounted for.

To complement routine surveillance, the detection of immune responses in serum has been used for many years to determine population infection levels for a wide range of pathogens. However, determining an individual’s infection status and when they become infected is a complex challenge that depends on various factors, including human, virological, and environmental interactions. This information is crucial to assess the risk of transmission, yet studying the immunological status of affected populations remains a challenging task that requires financial, human, and material resources that are rarely available in affected countries.

Recent technological advances have transformed sero-epidemiology into a powerful tool that bridges the gap between epidemiology, mathematical modeling, and public health to support risk reduction strategies. The Epidemiology and Public Health Unit is currently developing several population-based serological surveys at different scales to estimate the burden of infection, reconstruct the history of spatiotemporal transmission dynamics, and map infection risks at high resolution. These surveys will inform and guide precision public health strategies to combat priority infectious diseases effectively.

Organigram chart of the Unit

Our News

Recent Publications

Previous Publications

Antibody fucosylation predicts disease severity in secondary dengue infection

Stylianos Bournazos, Hoa Thi My Vo, Veasna Duong, Heidi Auerswald, Sowath Ly, Anavaj Sakuntabhai, Philippe Dussart, Tineke Cantaert**, Jeffrey V. Ravetch**

Science. American Association for the Advancement of Science; 2021;372(6546):11025. DOI: 10.1126/science.abc7303


Choosing interventions to eliminate forest malaria: preliminary results of two operational research studies inside Cambodian forests

Amber Kunkel, Chea Nguon, Sophea Iv, Srean Chhim, Dom Peov, Phanith Kong, Saorin Kim, Sarun Im, Mark Debackere, Nimol Khim, Jean Popovici, Sreynet Srun, Amélie Vantaux, Jean-Olivier Guintran, Benoit Witkowski, Patrice Piola.

Malar J. 2021;20(1):51. DOI: 10.1186/s12936-020-03572-3


Circulation of Bordetella pertussis in vaccinated Cambodian children: a transversal serological study

Gaelle Noel*, Laurence Borand*, Chanthy Leng, Chanthy Keang, Chhunly Botr, Bunnet Dim, Alexandra Kerleguer, Yik S. Peng, Navin Sreng, Vichit Ork, Mohand Ait-Ahmed, Nicole Guiso, Fabien Taieb.

Int J Infect Dis. 2021; DOI: 10.1016/j.ijid.2021.03.054


“Health in” and “Health of” Social-Ecological Systems: A Practical Framework for the Management of Healthy and Resilient Agricultural and Natural Ecosystems

Michel De Garine-Wichatitsky, Aurélie Binot, John Ward, Alexandre Caron, Arthur Perrotton, Helen Ross, Hoa Tran Quoc, Hugo Valls-Fox, Iain J. Gordon, Panomsak Promburom, Rico Ancog, Richard Anthony Kock, Serge Morand, Véronique Chevalier, Will Allen, Waraphon Phimpraphai, Raphaël Duboz, Pierre Echaubard.

Frontiers in Public Health 2021; 8:616328. DOI: 10.3389/fpubh.2020.616328


Host-Feeding Preference and Diel Activity of Mosquito Vectors of the Japanese Encephalitis Virus in Rural Cambodia

Sébastien Boyer, Benoit Durand, Sony Yean, Cécile Brengues, Pierre-Olivier MaquartDidier FontenilleVéronique Chevalier.

Pathogens. 2021;10(3):376. DOI: 10.3390/pathogens10030376


Impact of systematic early tuberculosis detection using Xpert MTB/RIF Ultra in children with severe pneumonia in high tuberculosis burden countries (TB-Speed pneumonia): a stepped wedge cluster randomized trial

Aurélia Vessière, Hélène Font, Delphine Gabillard, Laurence Adonis-Koffi, Laurence Borand, Chishala Chabala, Celso Khosa, Sandra Mavale, Raoul Moh, Veronica Mulenga, Juliet Mwanga-Amumpere, Jean-Voisin Taguebue, Mao Tan Eang, Christophe Delacourt, James A. Seddon, Manon Lounnas, Sylvain Godreuil, Eric Wobudeya, Maryline Bonnet, Olivier Marcy.

BMC Pediatr. 2021;21(1):136. DOI: 10.1186/s12887-021-02576-5


In-field Evaluation of SD Bioline HBsAg Whole Blood Rapid Test in Pregnant Women in Cambodia: the ANRS 12345 TA PROHM Study

Olivier Segeral, Wathanakpiseychoupoan Phirum, Ousa Khan, Hyna Chea, Saren Sovann, Sovann Nhoeung, Kearena Chhim, Song Yin, Bunnet Dim, Chantana Yay, Denis Laurent, Samsorphea Chhun, Laurence Borand.

Diagn Microbiol Infect Dis. 2021;101(2):115452. DOI: 10.1016/j.diagmicrobio.2021.115452


Large scale dog population demography, dog management and bite risk factors analysis: A crucial step towards rabies control in Cambodia

Véronique Chevalier, Holl Davun, Sopheak Sorn, Pitou Ly, Vutha Pov, Sowath Ly.

PLoS One. 2021;16(7):e0254192. DOI: 10.1371/journal.pone.0254192


Longitudinal monitoring in Cambodia suggests higher circulation of alpha and betacoronaviruses in juvenile and immature bats of three species

Julien Cappelle, Neil Furey, Thavry Hoem, Tey Putita Ou, Thona Lim, Vibol Hul, Oudam Heng, Véronique Chevalier, Philippe Dussart, Veasna Duong.

Sci Rep. 2021;11(1):24145. DOI: 10.1038/s41598-021-03169-z


Malaria in Cambodia: A Retrospective Analysis of a Changing Epidemiology 2006–2019

Srean Chhim, Patrice Piola, Tambri Housen, Vincent Herbreteau, Bunkea Tol.

Int J Environ Res Public Health. 2021;18(4). DOI: 10.3390/ijerph18041960


Mosquito Vector Competence for Japanese Encephalitis Virus

Heidi AuerswaldPierre-Olivier MaquartVéronique ChevalierSebastien Boyer.

Viruses. 2021;13(6):1154. DOI: 10.3390/v13061154


Novel anti-malarial drug strategies to prevent artemisinin partner drug resistance: A model-based analysis

Amber Kunkel, Michael White, Patrice Piola.

PLoS Comput Biol. 2021;17(3):e1008850. DOI: 10.1371/journal.pcbi.1008850


Phenotypic and genetic characterization of MERS coronaviruses from Africa to understand their zoonotic potential

Ziqi Zhou, Kenrie P. Y. Hui, Ray T. Y. So, Huibin Lv, Ranawaka A. P. M. Perera, Daniel K. W. Chu, Esayas Gelaye, Harry Oyas, Obadiah Njagi, Takele Abayneh, Wilson Kuria, Elias Walelign, Rinah Wanglia, Ihab El Masry, Sophie Von Dobschuetz, Wantanee Kalpravidh, Véronique Chevalier, Eve Miguel, Ouafaa Fassi-Fihri, Amadou Trarore, Weiwen Liang, Yanqun Wang, John M. Nicholls, Jincun Zhao, Michael C. W. Chan, Leo L. M. Poon, Chris Ka Pun Mok, Malik Peiris.

Proc Natl Acad Sci U S A. 2021;118(25):e2103984118. DOI: 10.1073/pnas.2103984118


Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal

Yu-Jin Jung, Bich-Tram Huynh, Abdoulaye Seck, Raymond Bercion, Fatoumata Diene Sarr, Perlinot Herindrainy, Jean-Baptiste Diouf, Zafitsara Zo Andrianirina, Arnaud Firon, Patrick Trieu-Cuot, Sophie Goyet, Jean-Marc Collard, Elisabeth Delarocque-Astagneau, Didier Guillemot**, Muriel Vray** and BIRDY Study Group.

The American Journal of Tropical Medicine and Hygiene; 2021;105(5):133946. DOI: 10.4269/ajtmh.21-0113


Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study

Bich-Tram Huynh, Elsa Kermorvant-Duchemin, Rattanak Chheang, Frederique Randrianirina, Abdoulaye Seck, Elisoa Hariniaina Ratsima, Zafitsara Zo Andrianirina, Jean-Baptiste Diouf, Armya Youssouf Abdou, Sophie Goyet, Véronique Ngo, Siyin Lach, Long Pring, Touch Sok, Michael Padget, Fatoumata Diene Sarr, Laurence Borand, Benoit Garin, Jean-Marc Collard, Perlinot Herindrainy, Agathe de Lauzanne, Muriel Vray, Elisabeth Delarocque-Astagneau, Didier Guillemot, On behalf of the BIRDY study Group.

PLOS Medicine. Public Library of Science; 2021;18(9):e1003681. DOI: 10.1371/journal.pmed.1003681


Tuberculosis Diagnosis in HIV-Infected Children: Comparison of the 2012 and 2015 Clinical Case Definitions for Classification of Intrathoracic Tuberculosis Disease

Olivier Marcy, Sophie Goyet, Laurence Borand, Philippe Msellati, Vibol Ung, Mathurin Tejiokem, Giang Do Chau, Francis Ateba-Ndongo, Abdoul Salam Ouedraogo, Bunnet Dim, Paul Perez, Julien Asselineau, Guislaine Carcelain, Stéphane Blanche, Christophe Delacourt, Sylvain Godreuil.

Journal of the Pediatric Infectious Diseases Society. 2021;piab113. DOI: 10.1093/jpids/piab113

Autoantibody Profiling in Plasma of Dengue Virus-Infected Individuals.

Vo Hoa Thi MyDuong VeasnaLy Sowath,Li, Quan-Zhen, Dussart PhilippeCantaert Tineke.

Pathogens. 2020;9(12). DOI: 10.3390/pathogens9121060


Comparison of Japanese Encephalitis Force of Infection in Pigs, Poultry and Dogs in Cambodian Villages

Ladreyt Héléna,Auerswald Heidi, Tum Sothyra, Ken SreymomHeng LeangyiIn SaradenLay SokcheaTop ChakriyouthLy Sowath, Duong Veasna, Dussart Philippe, Durand Benoit, Chevalier Véronique.

Pathogens. Multidisciplinary Digital Publishing Institute; 2020;9(9):719. DOI: 10.3390/pathogens9090719


Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

Upasani Vinit, Scagnolari Carolina; Frasca Federica,  Smith Nikaïa,  Bondet Vincent,  Vanderlinden Axelle,  Lay Sokchea,  Auerswald Heidi,  Heng Sothy,  Laurent Denis,  Ly Sowath,  Duong Veasna,  Antonelli Guido,  Dussart Philippe,  Duffy Darragh,  Cantaert Tineke.

Front Immunol. 2020;11:605087. DOI: 10.3389/fimmu.2020.605087


Dynamics and diversity of mosquito vectors of Japanese encephalitis virus in Kandal province, Cambodia

Boyer SebastienPeng BorinPang SenglongChevalier VéroniqueDuong VeasnaGorman ChristopherDussart Philippe, Fontenille Didier, Cappelle Julien.

Journal of Asia-Pacific Entomology. 2020;23(4):1048‑54. DOI: 10.1016/j.aspen.2020.08.018


Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis

Saito Makoto, Mansoor Rashid, Kennon Kalynn, Anvikar Anupkumar R, Ashley Elizabeth A, Chandramohan Daniel, Cohee Lauren M, D’Alessandro Umberto, Genton Blaise, Gilder Mary Ellen, Juma Elizabeth, Kalilani-Phiri Linda, Kuepfer Irene, Laufer Miriam K, Lwin Khin Maung, Meshnick Steven R, Mosha Dominic, Mwapasa Victor, Mwebaza Norah, Nambozi Michael, Ndiaye Jean-Louis A, Nosten François, Nyunt Myaing, Ogutu Bernhards, Parikh Sunil, Paw Moo Kho, Phyo Aung Pyae, Pimanpanarak Mupawjay, Piola Patrice, Rijken Marcus J, Sriprawat Kanlaya, Tagbor Harry K, Tarning Joel, Tinto Halidou, Valéa Innocent, Valecha Neena, White Nicholas J, Wiladphaingern Jacher, Stepniewska Kasia, McGready Rose, Guérin Philippe J. 

Lancet Infect Dis. 2020;20(8):943‑52. DOI: 10.1016/S1473-3099(20)30064-5


Frequency, risk factors, and complications of induced abortion in ten districts of Madagascar: results from a cross-sectional household survey

Ratovoson Rila, Kunkel Amber, Rakotovao Jean Pierre, Pourette Dolores, Mattern Chiarella, Andriamiadana Jocelyne, Harimanana Aina, Piola Patrice.

BMC Women’s Health, 05/06/2020 ; doi: 10.1186/s12905-020-00962-2


Hepatitis B e Antigen (HBeAg) Rapid Test and Alanine Aminotransferase Level–Based Algorithm to Identify Pregnant Women at Risk of HBV Mother-to-Child Transmission: The ANRS 12345 TA PROHM Study

Segeral Olivier, Dim Bunnet, Durier Christine, Prak Sophearot, Chhim Kearena, Vong Chanlina, Pech Sothy, Tiv Say, Nem Bunthoeun, Hout Kay, Nouhin Janin, Chhun Samsorphea, Borand Laurence.

Clinical Infectious Diseases. 2020;ciaa282. DOI: 10.1093/cid/ciaa282


Klebsiella pneumoniae carriage in low-income countries: antimicrobial resistance, genomic diversity and risk factors

Huynh Bich-Tram, Passet Virginie, Rakotondrasoa Andriniaina, Diallo Thierno, Kerleguer Alexandra, Hennart Melanie, Lauzanne Agathe De, Herindrainy Perlinot, Seck Abdoulaye, Bercion Raymond, Borand Laurence, Pardos de la Gandara Maria, Delarocque-Astagneau Elisabeth, Guillemot Didier, Vray Muriel, Garin Benoit, Collard Jean-Marc, Rodrigues Carla, Brisse Sylvain.

Gut Microbes. 2020;11(5):1287‑99. DOI: 10.1080/19490976.2020.1748257


Mortality Among People With HIV Treated for Tuberculosis Based on Positive, Negative, or No Bacteriologic Test Results for Tuberculosis: The IeDEA Consortium

Humphrey John M, Mpofu Philani, Pettit April C, Musick Beverly, Carter E Jane, Messou Eugène, Marcy Olivier, Crabtree-Ramirez Brenda, Yotebieng Marcel, Anastos Kathryn, Sterling Timothy R, Yiannoutsos Constantin, Diero Lameck, Wools-Kaloustian Kara.

Open Forum Infectious Diseases. 2020;7(1):ofaa006. DOI: 10.1093/ofid/ofaa006


Nipah virus circulation at human–bat interfaces, Cambodia

Cappelle Julien, Hoem ThavryHul Vibol, Furey Neil, Nguon Kunthy, Prigent Steven, Dupon Liane, Ken SreymomNeung ChhoeuthHok VisalPring LongLim Thona, Bumrungsri Sara, Duboz Raphaël, Buchy Philippe, Ly SowathDuong Veasna, Tarantola Arnaud, Binot Aurélie, Dussart Philippe.

Bull World Health Organ. 2020;98(8):539‑47. DOI: 10.2471/BLT.20.254227


Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

Saito Makoto, Mansoor Rashid, Kennon Kalynn, Anvikar Anupkumar R., Ashley Elizabeth A., Chandramohan Daniel, Cohee Lauren M., D’Alessandro Umberto, Genton Blaise, Gilder Mary Ellen, Juma Elizabeth, Kalilani-Phiri Linda, Kuepfer Irene, Laufer Miriam K., Lwin Khin Maung, Meshnick Steven R., Mosha Dominic, Muehlenbachs Atis, Mwapasa Victor, Mwebaza Norah, Nambozi Michael, Ndiaye Jean-Louis A., Nosten François, Nyunt Myaing, Ogutu Bernhards, Parikh Sunil, Paw Moo Kho, Phyo Aung Pyae, Pimanpanarak Mupawjay, Piola Patrice, Rijken Marcus J., Sriprawat Kanlaya, Tagbor Harry K., Tarning Joel, Tinto Halidou, Valéa Innocent, Valecha Neena, White Nicholas J., Wiladphaingern Jacher, Stepniewska Kasia, McGready Rose, Guérin Philippe J.

BMC Med. 2020;18(1):138. DOI: 10.1186/s12916-020-01592-z


Remote Sensing and Multi-Criteria Evaluation for Malaria Risk Mapping to Support Indoor Residual Spraying Prioritization in the Central Highlands of Madagascar

Rakotoarison Hobiniaina Anthonio, Rasamimalala Mampionona, Rakotondramanga Jean Marius, Ramiranirina Brune, Franchard Thierry, Kapesa Laurent, Razafindrakoto Jocelyn, Guis Hélène, Tantely Luciano Michaël, Girod Romain, Rakotoniaina Solofoarisoa, Baril Laurence, Piola Patrice, Rakotomanana Fanjasoa.

Remote Sensing. Multidisciplinary Digital Publishing Institute; 2020;12(10):1585. DOI: 10.3390/rs12101585


School-Based Serosurveys to Assess the Validity of Using Routine Health Facility Data to Target Malaria Interventions in the Central Highlands of Madagascar

Steinhardt Laura C., Ravaoarisoa Elisabeth, Wiegand Ryan, Harimanana Aina, Hedje Judith, Cotte Annett H., Zigirumugabe Sixte, Kesteman Thomas, Rasoloharimanana Tsikiniaina L., Rakotomalala Emma, Randriamoramanana Anny M., Rakotondramanga Jean-Marius, Razanatsiorimalala Seheno, Mercereau-Puijalon Odile, Perraut Ronald, Ratsimbasoa Arsène, Butts Jessica, Rogier Christophe, Piola Patrice, Randrianarivelojosia Milijaona, Vigan-Womas Inès.

J Infect Dis. 2020; DOI: 10.1093/infdis/jiaa476


Serological Evidence for Japanese Encephalitis and West Nile Virus Infections in Domestic Birds in Cambodia

Auerswald HeidiRuget Anne-Sophie, Ladreyt Helena, In SaradenMao Sokthearom, Sorn San, Tum Sothyra, Duong VeasnaDussart PhilippeCappelle Julien**, Chevalier Véronique**

Front Vet Sci. 2020;7:15. DOI: 10.3389/fvets.2020.00015


Serological Evidence of West Nile and Usutu Viruses Circulation in Domestic and Wild Birds in Wetlands of Mali and Madagascar in 2008

Chevalier Véronique, Marsot Maud, Molia Sophie, Rasamoelina Harena, Rakotondravao René, Pedrono Miguel, Lowenski Steeve, Durand Benoit, Lecollinet Sylvie, Beck Cécile.

IJERPH. 2020;17(6):1998. DOI: 10.3390/ijerph17061998


Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults

Blanc François-Xavier, Badje Anani D., Bonnet Maryline, Gabillard Delphine, Messou Eugène, Muzoora Conrad, Samreth Sovannarith, Nguyen Bang D., Borand Laurence, Domergue Anaïs, Rapoud Delphine, Natukunda Naome, Thai Sopheak, Juchet Sylvain, Eholié Serge P., Lawn Stephen D., Domoua Serge K., Anglaret Xavier, Laureillard Didier.

N Engl J Med. 2020;382(25):2397‑410. DOI: 10.1056/NEJMoa1910708


Tools to accelerate falciparum malaria elimination in Cambodia: a meeting report

Lek Dysoley, Callery James J., Nguon Chea, Debackere Mark, Sovannaroth Siv, Tripura Rupam, Wojnarski Marius, Piola Patrice, Khean Soy Ty, Manion Kylie, Nguon Sokomar, Kunkel Amber, Vernaeve Lieven, Peto Thomas J., Dantzer Emily, Davoeung Chan, Etienne William, Dondorp Arjen M., Tuseo Luciano, von Seidlein Lorenz, Guintran Jean-Olivier.

Malar J. 2020;19(1):151. DOI: 10.1186/s12936-020-03197-6



A 1-week intradermal dose-sparing regimen for rabies post-exposure prophylaxis (RESIST-2): an observational cohort study

Tineke CantaertLaurence BorandLauriane KergoatChanthy LengSivlin UngSotheary InYiksing PengChandara PhoeunChanthy HingChun Navy TaingManil SamanSivuth OngChanna MeyRithy ChoeungSowath LyPhilippe Dussart, Hervé Bourhy, Arnaud Tarantola.

Lancet Infect Dis. 2019;19(12):1355‑62. DOI: 10.1016/S1473-3099(19)30311-1


A multi-country study of the economic burden of dengue fever based on patient-specific field surveys in Burkina Faso, Kenya, and Cambodia

Jung-Seok Lee, Vittal Mogasale, Jacqueline K. Lim, Sowath Ly, Kang Sung Lee, Sopheak Sorn, Esther Andia, Mabel Carabali, Suk Namkung, Sl-Ki Lim, Valéry Ridde, Sammy M. Njenga, Seydou Yaro, In-Kyu Yoon.

PLOS Neglected Tropical Diseases. Public Library of Science; 2019;13(2):e0007164. DOI: 10.1371/journal.pntd.0007164


A Novel Polycipiviridae Virus Identified in Pteropus lylei Stools

Sarah Temmam, Vibol Hul, Thomas Bigot, Thavry Hoem, Christopher Gorman, Veasna Duong, Philippe Dussart, Julien Cappelle, Marc Eloit. Matthijnssens J, directeur.

Microbiol Resour Announc. 2019;8(15):e01662-18. DOI: 10.1128/MRA.01662-18


Antimicrobial resistance in Cambodia: a review

Thomas A. N. Reed, Sidonn Krang, Thyl Miliya, Nicola Townell, Joanne Letchford, Sreng Bun, Borann Sar, Kristina Osbjer, Sokerya Seng, Monidarin Chou, Youlet By, Lkhagvadorj Vanchinsuren, Vandarith Nov, Darapheak Chau, Thong Phe, Agathe de Lauzanne, Sovann Ly, Paul Turner, Cambodia Technical Working Group on Antimicrobial Resistance.

Int J Infect Dis. 2019;85:98‑107. DOI: 10.1016/j.ijid.2019.05.036


A Treatment-Decision Score for HIV-Infected Children With Suspected Tuberculosis

Olivier Marcy, Laurence Borand, Vibol Ung, Philippe Msellati, Mathurin Tejiokem, Khanh Truong Huu, Viet Do Chau, Duong Ngoc Tran, Francis Ateba-Ndongo, Suzie Tetang-Ndiang, Boubacar Nacro, Bintou Sanogo, Leakhena Neou, Sophie Goyet, Bunnet Dim, Polidy Pean, Catherine Quillet, Isabelle Fournier, Laureline Berteloot, Guislaine Carcelain, Sylvain Godreuil, Stéphane Blanche, Christophe Delacourt, ANRS 12229 PAANTHER 01 STUDY GROUP.

Pediatrics. 2019;144(3):e20182065. DOI: 10.1542/peds.2018-2065


Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013

Sowath LyCamille FortasVeasna Duong, Tarik Benmarhnia, Anavaj Sakuntabhai, Richard Paul, Rekol Huy, Sopheak SornKunthy NguonSiam ChanSouv KimsanSivuth Ong, Kim Srorn Kim, Sowathy Buoy, Lim Voeung, Philippe DussartPhilippe BuchyArnaud Tarantola.

Emerging Infectious Diseases, 07/2019 ; DOI:10.3201/eid2507.181794


CTX-M-55-type ESBL-producing Salmonella enterica are emerging among retail meats in Phnom Penh, Cambodia

Maya Nadimpalli, Laetitia Fabre, Vuthy Yith, Nita Sem, Malika Gouali, Elisabeth Delarocque-Astagneau, Navin Sreng, Simon Le Hello, the BIRDY study group.

Journal of Antimicrobial Chemotherapy. 2019;74(2):342‑8. DOI: 10.1093/jac/dky451


Diagnosis and management of latent tuberculosis infection in Asia: Review of current status and challenges

Nicholas I. Paton, Laurence Borand, Jubert Benedicto, Mar Mar Kyi, Asif Mujtaba Mahmud, Mohd Nor Norazmi, Nandini Sharma, Charoen Chuchottaworn, Yi-Wen Huang, Nastiti Kaswandani, Hoi Le Van, Grace C.Y. Lui, Tan Eang Mao.

International Journal of Infectious Diseases. 2019;87:21‑9. DOI: 10.1016/j.ijid.2019.07.004


Diversity of Dromedary Camel Coronavirus HKU23 in African Camels Revealed Multiple Recombination Events among Closely Related Betacoronaviruses of the Subgenus Embecovirus

Ray T. Y. So, Daniel K. W. Chu, Eve Miguel, Ranawaka A. P. M. Perera, Jamiu O. Oladipo, Ouafaa Fassi-Fihri, Gelagay Aylet, Ronald L. W. Ko, Ziqi Zhou, Mo-Sheung Cheng, Sulyman A. Kuranga, François L. Roger, Veronique Chevalier, Richard J. Webby, Patrick C. Y. Woo, Leo L. M. Poon, Malik Peiris.

Journal of Virology. American Society for Microbiology 93(23):e01236-19. DOI: 10.1128/JVI.01236-19


Escherichia coli ST410 among humans and the environment in Southeast Asia

Maya L. Nadimpalli, Agathe de Lauzanne, Thong Phe, Laurence Borand, Jan Jacobs, Laetitia Fabre, Thierry Naas, Simon Le Hello, Marc Stegger.

International Journal of Antimicrobial Agents. 2019;54(2):228‑32. DOI: 10.1016/j.ijantimicag.2019.05.024


Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon

Chavely Gwladys Monamele, Phalla Y., Erik Albert Karlsson, Marie-Astrid Vernet, Abel Wade, Marie-Claire Assoumou Okomo, Aristide Stéphane Abah Abah, Sokhoun Yann, Georges Alain Mballa Etoundi, Njankouo Ripa Mohamadou, Jean-Marc Feussom, Sreyviseth HormPaul Francis HorwoodSowath Ly, Richard Njouom, Philippe Dussart.

Emerging Microbes & Infections. 2019;8(1):186‑96. DOI: 10.1080/22221751.2018.1564631


High Activation of γδ T Cells and the γδ2pos T-Cell Subset Is Associated With the Onset of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome, ANRS 12153 CAPRI NK

Polidy PeanJanin NouhinMeng Ratana, Yoann Madec, Laurence Borand, Olivier Marcy, Didier Laureillard, Marcelo Fernandez, Françoise Barré-Sinoussi, Laurence Weiss, Daniel Scott-Algara.

Front Immunol. 2019;10:2018. DOI: 10.3389/fimmu.2019.02018


How Central Is the Domestic Pig in the Epidemiological Cycle of Japanese Encephalitis Virus? A Review of Scientific Evidence and Implications for Disease Control

Héléna Ladreyt, Benoit Durand, Philippe DussartVéronique Chevalier

Viruses. Multidisciplinary Digital Publishing Institute; 2019;11(10):949. DOI: 10.3390/v11100949


Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection

Vinit UpasaniHoa Thi My VoSivlin Ung, Sothy Heng, Denis Laurent, Rithy ChoeungVeasna DuongSopheak SornSowath Ly, Izabela A. Rodenhuis-Zybert, Philippe DussartTineke Cantaert.

Front Immunol. 2019;10:2500. DOI: 10.3389/fimmu.2019.02500


Insights into the Host Range, Genetic Diversity, and Geographical Distribution of Jingmenviruses

Sarah Temmam, Thomas Bigot, Delphine Chrétien, Mathilde Gondard, Philippe Pérot, Virginie Pommelet, Evelyne Dufour, Stéphane Petres, Elodie Devillers, Thavry Hoem, Valérie Pinarello, Vibol Hul, Khamsing Vongphayloth, Jeffrey C. Hertz, Irène Loiseau, Marine Dumarest, Veasna Duong, Muriel Vayssier-Taussat, Marc Grandadam, Emmanuel Albina, Philippe Dussart, Sara Moutailler, Julien Cappelle, Paul T. Brey, Marc Eloit.

mSphere. American Society for Microbiology 4(6):e00645-19. DOI: 10.1128/mSphere.00645-19


Intradermal rabies post-exposure prophylaxis can be abridged with no measurable impact on clinical outcome in Cambodia, 2003-2014

Arnaud TarantolaSowath LyMalen ChanSotheary InYiksing PengChanthy HingChun Navy TaingChandara Phoen, Sovann Ly, Simon Cauchemez, Philippe Buchy, Philippe Dussart, Hervé Bourhy, Jean-Yves Mary.

Vaccine. 2019;37 Suppl 1:A118‑27. DOI: 10.1016/j.vaccine.2018.10.054


Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis

Laurence Borand*, Agathe de Lauzanne*, Ngoc Lan Nguyen, Sokleaph Cheng, Thu Hang Pham, Sara Eyangoh, Abdoul-Salam Ouedraogo, Vibol Ung, Philippe Msellati, Mathurin Tejiokem, Boubacar Nacro, Malin Inghammar, Bunnet Dim, Christophe Delacourt, Sylvain Godreuil, Stéphane Blanche**, Olivier Marcy**, Pediatric Asian African Network for Tuberculosis and HIV Research (PAANTHER) Study Group.

Clin Infect Dis. 2019;68(10):1750‑3. DOI: 10.1093/cid/ciy897


Meat and Fish as Sources of Extended-Spectrum ?-Lactamase–Producing Escherichia coli, Cambodia

Maya Nadimpalli, Yith Vuthy, Agathe de Lauzanne, Laetitia Fabre, Alexis Criscuolo, Malika Gouali, Bich-Tram Huynh, Thierry Naas, Thong Phe, Laurence Borand, Jan Jacobs, Alexandra Kerléguer, Patrice Piola, Didier Guillemot, Simon Le Hello, Elisabeth Delarocque-Astagneau, on behalf of the BIRDY study group.

Emerg Infect Dis. 2019;25(1). DOI: 10.3201/eid2501.180534


Predicting Dengue Outbreaks in Cambodia

Anthony CousienJulia LedienKimsan Souv, Rithea Leang, Rekol Huy, Didier FontenilleSowath LyVeasna DuongPhilippe DussartPatrice Piola**, Simon Cauchemez**, Arnaud Tarantola**.

Emerging Infectious Diseases, 12/2019 ; DOI:10.3201/eid2512.181193


Pteropus lylei primarily forages in residential areas in Kandal, Cambodia

Kinley Choden*, Sébastien Ravon*, Jonathan H. Epstein, Thavry Hoem, Neil Furey, Marie Gely, Audrey Jolivot, Vibol HulChhoeuth Neung, Annelise Tran, Julien Cappelle.

Ecology and Evolution. 2019;9(7):4181‑91. DOI: 10.1002/ece3.5046



Publications in journals without Impact Factor in 2019


A Novel Polycipiviridae Virus Identified in Pteropus lylei Stools

Sarah Temmam, Vibol Hul, Thomas Bigot, Thavry Hoem, Christopher Gorman, Veasna Duong, Philippe Dussart, Julien Cappelle, Marc Eloit.

Microbiol Resour Announc. 2019;8(15):e01662-18. DOI: 10.1128/MRA.01662-18


Acquisition of extended spectrum beta-lactamase-producing enterobacteriaceae in neonates: A community based cohort in Madagascar

Perlinot Herindrainy, Mamitiana Alain Noah Rabenandrasana, Zafitsara Zo Andrianirina, Feno Manitra Jacob Rakotoarimanana, Michael Padget, Agathe de Lauzanne, Awa Ndir, Elsa Kermorvant-Duchemin, Benoit Garin, Patrice Piola, Jean-Marc Collard, Didier Guillemot, Bich-Tram Huynh, Elisabeth Delarocque-Astagneau, for the BIRDY study Group.

PLOS ONE. Public Library of Science; 2018;13(3):e0193325. DOI: 10.1371/journal.pone.0193325



Beta-lactam resistance among Enterobacteriaceae in Cambodia: The four-year itch

Yannick CaronRattanak ChheangNop PutheaMeng SodaSébastien BoyerArnaud TarantolaAlexandra Kerléguer.

Int J Infect Dis. 2018;66:74‑9. DOI: 10.1016/j.ijid.2017.10.025


Broad and long-lasting immune protection against various Chikungunya genotypes demonstrated by participants in a cross-sectional study in a Cambodian rural community

Heidi AuerswaldCamille BoussiouxSaraden InSokthearom MaoSivuth OngRekol HuyRithea LeangMalen ChanVeasna DuongSowath LyArnaud TarantolaPhilippe Dussart.

Emerging Microbes & Infections. Taylor & Francis; 2018;7(1):1‑13. DOI: 10.1038/s41426-017-0010-0


Co-circulation of Influenza A H5, H7, and H9 Viruses and Co-infected Poultry in Live Bird Markets, Cambodia

Paul F. HorwoodSrey Viseth HormAnnika SuttieSopheak ThetPhalla YSareth Rith, San Sorn, Davun Holl, Sothyra Tum, Sowath LyErik A. KarlssonArnaud TarantolaPhilippe Dussart.

Emerg Infect Dis. 2018;24(2):352‑5. DOI: 10.3201/eid2402.171360


Combating Global Antibiotic Resistance: Emerging One Health Concerns in Lower- and Middle-Income Countries

Maya Nadimpalli, Elisabeth Delarocque-Astagneau, David C. Love, Lance B. Price, Bich-Tram Huynh, Jean-Marc Collard, Kruy Sun Lay, Laurence Borand, Awa Ndir, Timothy R. Walsh, Didier Guillemot, Bacterial Infections and antibiotic-Resistant Diseases among Young children in low-income countries (BIRDY) Study Group.

Clin Infect Dis. 2018;66(6):963‑9. DOI: 10.1093/cid/cix879


Community-acquired pneumonia and Gram-negative bacilli in Cambodia—incidence, risk factors and clinical characteristics

Malin Inghammar, Laurence Borand, Sophie Goyet, Blandine Rammaert, Vantha Te, Patrich Lorn Try, Bertrand Guillard, Philippe Buchy, Sirenda Vong, Eap Tek Chheng, Philippe Cavailler, Charles Mayaud, Arnaud Tarantola.

Transactions of The Royal Society of Tropical Medicine and Hygiene. 2018;112(2):57‑63. DOI: 10.1093/trstmh/try022


Comparison of the dynamics of Japanese encephalitis virus circulation in sentinel pigs between a rural and a peri-urban setting in Cambodia

Juliette Di FrancescoRithy ChoeungBorin Peng, Long Pring, Senglong PangRaphaël DubozSivuth Ong, San Sorn, Arnaud TarantolaDidier FontenilleVeasna DuongPhilippe DussartVéronique ChevalierJulien Cappelle.

PLOS Neglected Tropical Diseases. Public Library of Science; 2018;12(8):e0006644. DOI: 10.1371/journal.pntd.0006644


Declining hepatitis E virus antibody prevalence in Phnom Penh, Cambodia during 1996-2017

Nouhin, Y. Madec, S. PrakM. OrkA. KerleguerY. Froehlich, N. Pavio, F. Rouet.

Epidemiol Infect. 2018;147:e26. DOI: 10.1017/S0950268818002790


Dengue modeling in rural Cambodia: Statistical performance versus epidemiological relevance

Clara Champagne, Richard Paul, Sowath LyVeasna Duong, Rithea Leang, Bernard Cazelles.

Epidemics. 2019;26:43‑57. DOI: 10.1016/j.epidem.2018.08.004


Differential replication efficiencies between Japanese encephalitis virus genotype I and III in avian cultured cells and young domestic ducklings

Changguang Xiao, Chenxi Li, Di Di, Julien Cappelle, Lihong Liu, Xin Wang, Linlin Pang, Jinpeng Xu, Ke Liu, Beibei Li, Donghua Shao, Yafeng Qiu, Weijie Ren, Frederik Widén, Véronique Chevalier, Jianchao Wei, Xiaodong Wu, Zhiyong Ma.

PLOS Neglected Tropical Diseases. Public Library of Science; 2018;12(12):e0007046. DOI: 10.1371/journal.pntd.0007046


How much does direct transmission between pigs contribute to Japanese Encephalitis virus circulation? A modelling approach in Cambodia

Alpha Oumar II Diallo, Véronique Chevalier, Julien Cappelle, Veasna Duong, Didier Fontenille, Raphaël Duboz.

PLOS ONE. Public Library of Science; 2018;13(8):e0201209. DOI: 10.1371/journal.pone.0201209


Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus–infected Children With Suspected Tuberculosis

Laurence Borand*, Agathe de Lauzanne*, Ngoc Lan Nguyen, Sokleaph Cheng, Thu Hang Pham, Sara Eyangoh, Abdoul-Salam Ouedraogo, Vibol Ung, Philippe Msellati, Mathurin Tejiokem, Boubacar Nacro, Malin Inghammar, Bunnet Dim, Christophe Delacourt, Sylvain Godreuil, Stéphane Blanche, Olivier Marcy.

Clin Infect Dis. 2019;68(10):1750‑3. DOI: 10.1093/cid/ciy897


Japanese encephalitis circulation pattern in swine of northern Vietnam and consequences for swine’s vaccination recommendations

A.-S. Ruget, C. Beck, A. Gabassi, K. Trevennec, S. Lecollinet, V. Chevalier, J. Cappelle.

Transbound Emerg Dis. 2018;65(6):1485‑92. DOI: 10.1111/tbed.12885


MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity

Daniel K. W. Chu, Kenrie P. Y. Hui, Ranawaka A. P. M. Perera, Eve Miguel, Daniela Niemeyer, Jincun Zhao, Rudragouda Channappanavar, Gytis Dudas, Jamiu O. Oladipo, Amadou Traoré, Ouafaa Fassi-Fihri, Abraham Ali, Getnet F. Demissié, Doreen Muth, Michael C. W. Chan, John M. Nicholls, David K. Meyerholz, Sulyman A. Kuranga, Gezahegne Mamo, Ziqi Zhou, Ray T. Y. So, Maged G. Hemida, Richard J. Webby, Francois Roger, Andrew Rambaut, Leo L. M. Poon, Stanley Perlman, Christian Drosten, Veronique Chevalier, Malik Peiris.

Proceedings of the National Academy of Sciences; 2018;115(12):3144‑9. DOI: 10.1073/pnas.1718769115


Mortality and its determinants in antiretroviral treatment-naive HIV-infected children with suspected tuberculosis: an observational cohort study

Olivier Marcy, Mathurin Tejiokem, Philippe Msellati, Khanh Truong Huu, Viet Do Chau, Duong Tran Ngoc, Boubacar Nacro, Francis Ateba-Ndongo, Suzie Tetang-Ndiang, Vibol Ung, Bunnet Dim, Leakhena Neou, Laureline Berteloot, Laurence Borand, Christophe Delacourt, Stéphane Blanche, ANRS 12229 PAANTHER 01 Study Group.

The Lancet HIV. Elsevier; 2018;5(2):e87‑95. DOI: 10.1016/S2352-3018(17)30206-0


Rabies Postexposure Prophylaxis Noncompletion After Dog Bites: Estimating the Unseen to Meet the Needs of the Underserved

Arnaud TarantolaSophie BlanchiJulien CappelleSowath LyMalen ChanSotheary InYiksing PengChanthy HingChun Navy Taing, Sovann Ly, Hervé Bourhy, Philippe Buchy, Philippe Dussart, Jean-Yves Mary.

American Journal of Epidemiology. 2018;187(2):306‑15. DOI: 10.1093/aje/kwx234


Serotype Distribution of Clinical Streptococcus pneumoniae Isolates before the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Cambodia

Malin Inghammar, Youlet By, Christina Farris, Thong Phe, Laurence Borand, Alexandra Kerleguer, Sophie Goyet, Vonthanak Saphonn, Chanleakhena Phoeung, Sirenda Vong, Blandine Rammaert, Charles Mayaud, Bertrand Guillard, Chadwick Yasuda, Matthew R. Kasper, Gavin Ford, Steven W. Newell, Ung Sam An, Buth Sokhal, Sok Touch, Paul Turner, Jan Jacobs, Mélina Messaoudi, Florence Komurian-Pradel, Arnaud Tarantola.                         

The American Journal of Tropical Medicine and Hygiene. 2018;98(3):791‑6. DOI: 10.4269/ajtmh.17-0692


The potential effect of improved provision of rabies post-exposure prophylaxis in Gavi-eligible countries: a modelling study

Katie Hampson, Francesco Ventura, Rachel Steenson, Rebecca Mancy, Caroline Trotter, Laura Cooper, Bernadette Abela-Ridder, Lea Knopf, Moniek Ringenier, Tenzin Tenzin, Sowath Ly, Arnaud Tarantola, Ronelngar Moyengar, Assandi Oussiguéré, Bassirou Bonfoh, DH Ashwath Narayana, Mysore Kalappa Sudarshan, Matthew Muturi, Athman Mwatondo, Gati Wambura, Soa Fy Andriamandimby, Laurence Baril, Glenn T Edosoa, Abdallah Traoré, Sarah Jayme, Johann Kotzé, Amila Gunesekera, Nakul Chitnis, Jan Hattendorf, Mirjam Laager, Monique Lechenne, Jakob Zinsstag, Joel Changalucha, Zac Mtema, Ahmed Lugelo, Kennedy Lushasi, Onphirul Yurachai, Charlotte Jessica E. Metcalf, Malavika Rajeev, Jesse Blanton, Galileu Barbosa Costa, Nandini Sreenivasan, Ryan Wallace, Deborah Briggs, Louise Taylor, Samuel M. Thumbi, Nguyen Thi Thanh Huong.

The Lancet Infectious Diseases. 2019;19(1):102‑11. DOI: 10.1016/S1473-3099(18)30512-7


Usefulness of a serial algorithm of HBsAg and HBeAg rapid diagnosis tests to detect pregnant women at risk of HBV mother-to-child transmission in Cambodia, the ANRS 12328 pilot study

Olivier Ségéral, Dieynaba S. N’DiayeSophearot PrakJanin Nouhin, Samsorphea Chhun, Wootichai Khamduang, Kenrena Chim, Anne-Marie Roque-Afonso, Patrice PiolaLaurence Borand, Nicole Ngo-Giang-Huong, François Rouet, ANRS 12328 12345 Study Group.

J Clin Virol. 2018;109:29‑34. DOI: 10.1016/j.jcv.2018.10.007


Value of chest X-ray in TB diagnosis in HIV-infected children living in resource-limited countries: the ANRS 12229-PAANTHER 01 study

Berteloot, O. Marcy, B. Nguyen, V. Ung, M. Tejiokem, B. Nacro, S. Goyet, B. Dim, S. Blanche, L. Borand, P. Msellati, C. Delacourt, for the ANRS 12229 PAANTHER 01 Study Group.

The International Journal of Tuberculosis and Lung Disease. 2018;22(8):844‑50. DOI: 10.5588/ijtld.18.0122

A prospective, comparative study of severe neurological and uncomplicated hand, foot and mouth forms of paediatric enterovirus 71 infections

Yoann CrabolPolidy PeanChanna MeyVeasna Duong, Beat Richner, Denis Laurent, Ky Santy, Heng Sothy, Philippe DussartArnaud TarantolaPhilippe Buchy**, Paul F. Horwood**.

Int J Infect Dis. 2017;59:69‑76. DOI: 10.1016/j.ijid.2017.04.005


Assessing the performance of remotely-sensed flooding indicators and their potential contribution to early warning for leptospirosis in Cambodia

Julia Ledien, Sopheak Sorn, Sopheak Hem, Rekol Huy, Philippe Buchy, Arnaud Tarantola, Julien Cappelle.

PLOS ONE. Public Library of Science; 2017;12(7):e0181044. DOI: 10.1371/journal.pone.0181044


Geographic variations of the bird-borne structural risk of West Nile virus circulation in Europe

Benoit Durand, Annelise Tran, Gilles Balança, Véronique Chevalier.

PLOS ONE. Public Library of Science; 2017;12(10):e0185962. DOI: 10.1371/journal.pone.0185962


Increased adaptive immune responses and proper feedback regulation protect against clinical dengue

Etienne Simon-Lorière, Veasna Duong, Ahmed Tawfik, Sivlin Ung, Sowath Ly, Isabelle Casadémont, Matthieu Prot, Noémie Courtejoie, Kevin Bleakley, Philippe Buchy, Arnaud Tarantola, Philippe Dussart, Tineke Cantaert, Anavaj Sakuntabhai.

Sci Transl Med. 2017;9(405). DOI: 10.1126/scitranslmed.aal5088


Interleukin-1 receptor antagonist, a biomarker of response to anti-TB treatment in HIV/TB co-infected patients

Janin Nouhin, Polidy Pean, Yoann Madec, Mathieu F. Chevalier, Celine Didier, Laurence Borand, François-Xavier Blanc, Daniel Scott-Algara, Didier Laureillard, Laurence Weiss.

J Infect. 2017;74(5):456‑65. DOI: 10.1016/j.jinf.2017.01.016


Isolation and full-genome sequences of Japanese encephalitis virus genotype I strains from Cambodian human patients, mosquitoes and pigs

Veasna Duong, Rithy Choeung, Christopher Gorman, Denis Laurent, Yoann Crabol, Channa Mey, Borin Peng, Juliette Di Francesco, Vibol Hul, Heng Sothy, Ky Santy, Beat Richner, Jean-David Pommier, San Sorn, Véronique Chevalier, Philippe Buchy, Xavier de Lamballerie, Julien Cappelle, Paul Francis Horwood, Philippe Dussart.

J Gen Virol. 2017;98(9):2287‑96. DOI: 10.1099/jgv.0.000892


Low Circulation of Zika Virus, Cambodia, 2007-2016

Veasna DuongSivuth Ong, Rithea Leang, Rekol Huy, Sowath LyUgo MounierTeyputita OuSaraden InBorin PengSreymom Ken, Philippe Buchy, Arnaud Tarantola, Paul F. HorwoodPhilippe Dussart.

Emerg Infect Dis. 2017;23(2):296‑9. DOI: 10.3201/eid2302.161432


Proteinuria during dengue fever in children

Anne-Claire AndriesVeasna DuongJulien CappelleSivuth OngAlexandra KerleguerSowath LyArnaud TarantolaPaul F. Horwood, Anavaj Sakuntabhai, Philippe DussartPhilippe Buchy.

Int J Infect Dis. 2017;55:38‑44. DOI: 10.1016/j.ijid.2016.12.022


Seroprevalence and Transmission of Human Influenza A(H5N1) Virus before and after Virus Reassortment, Cambodia, 2006–2014

Sowath Ly, Paul Horwood, Malen Chan, Sareth Rith, Sopheak Sorn, Kunthea Oeung, Kunthy Nguon, Siam Chan, Phalla Y, Amy Parry, Reiko Tsuyuoka, Sovann Ly, Beat Richner, Denis Laurent, Sirenda Vong, Philippe Dussart, Philippe Buchy, Arnaud Tarantola.

Emerg Infect Dis. 2017;23(2):300‑3. DOI: 10.3201/eid2302.161232

A confirmed rabies case in a French resident in Cambodia, June 2015

Arnaud TarantolaChanna MeySowath Ly, Cornelia Haener, Nareth Chhor, Uong Meng, Sovann Ly, Didier FontenillePhilippe Dussart.

Journal of Travel Medicine. 2016;23(2):tav012. DOI: 10.1093/jtm/tav012


An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

Rithea Leang, Naw Htee Khu, Mavuto Mukaka, Mark Debackere, Rupam Tripura, Soy Ty Kheang, Say Chy, Neeraj Kak, Philippe BuchyArnaud TarantolaDidier Menard, Arantxa Roca-Felterer, Rick M. Fairhurst, Sim Kheng, Sinoun Muth, Song Ngak, Arjen M. Dondorp, Nicholas J. White, Walter Robert John Taylor.

BMC Med. 2016;14(1):171. DOI: 10.1186/s12916-016-0701-8


A prospective study on the incidence of dog bites and management in a rural Cambodian, rabies-endemic setting

Aurelia Ponsich, Flavie Goutard, San Sorn, Arnaud Tarantola.

Acta Tropica. 2016;160:62‑7. DOI: 10.1016/j.actatropica.2016.04.015


Bacterial neonatal sepsis and antibiotic resistance in low-income countries

Bich-Tram Huynh, Michael Padget, Benoit Garin, Elisabeth Delarocque-Astagneau, Didier Guillemot, Laurence Borand, Thida Chon, Agathe de Lauzanne, Sophie Goyet, Sopheak Hem, Alexandra Kerleguer, Siyin Lach, Veronique Ngo, Arnaud Tarantola, Sok Touch, Jean-Marc Collard, Perlinot Herindrainy, Patrice Piola, Bodonirina Tanjona Raheliarivao, Frédérique Randrianirina, Awa Ndir, Vincent Richard, Abdoulaye Seck, Raymond Bercion, Amy Gassama Sow, Jean Baptiste Diouf, Pape Samba Dieye, Balla Sy, Bouya Ndao, Maud Seguy, Elsa Kermorvant-Duchemin, Laurence Watier.

The Lancet. Elsevier; 2016;387(10018):533‑4. DOI: 10.1016/S0140-6736(16)00220-8


Biodiversity and health: Lessons and recommendations from an interdisciplinary conference to advise Southeast Asian research, society and policy

Bruno Andreas Walther, Christophe Boëte, Aurélie Binot, Youlet By, Julien Cappelle, Juan Carrique-Mas, Monidarin Chou, Neil Furey, Sothea Kim, Claire Lajaunie, Sovan Lek, Philippe Méral, Malyne Neang, Boon-Huan Tan, Catherine Walton, Serge Morand.

Infect Genet Evol. 2016;40:29‑46. DOI: 10.1016/j.meegid.2016.02.003


Caring for patients with rabies in developing countries – the neglected importance of palliative care

Arnaud TarantolaYoann Crabol, Bangalore Jayakrishnappa Mahendra, Sotheary InHubert Barennes, Hervé Bourhy, Yiksing PengSowath LyPhilippe Buchy.

Tropical Medicine & International Health. 2016;21(4):564‑7. DOI: 10.1111/tmi.12670


Dyslipidemias and Elevated Cardiovascular Risk on Lopinavir-Based Antiretroviral Therapy in Cambodia

Setha Limsreng, Olivier Marcy, Sowath Ly, Vara Ouk, Hak Chanroeurn, Saem Thavary, Ban Boroath, Ana Canestri, Gérald Viretto, Jean-François Delfraissy, Olivier Ségéral.

PLOS ONE. Public Library of Science; 2016;11(8):e0160306. DOI: 10.1371/journal.pone.0160306


Early diagnosis of dengue disease severity in a resource-limited Asian country

Philippe Cavailler, Arnaud Tarantola, Yee Sin Leo, Andrew A. Lover, Anne Rachline, Moniboth Duch, Rekol Huy, Ai Li Quake, Yuvatha Kdan, Veasna Duong, Jeremy L. Brett, Philippe Buchy.

BMC Infectious Diseases. 2016;16(1):512. DOI: 10.1186/s12879-016-1849-8


Environmental contamination and risk factors for transmission of highly pathogenic avian influenza A(H5N1) to humans, Cambodia, 2006-2010

Sowath LySirenda VongPhilippe Cavailler, Elizabeth Mumford, Channa MeySareth RithMaria D. Van Kerkhove, San Sorn, Touch Sok, Arnaud Tarantola**, Philippe Buchy**.

BMC Infect Dis. 2016;16(1):631. DOI: 10.1186/s12879-016-1950-z


Estimating the Burden of Leptospirosis among Febrile Subjects Aged below 20 Years in Kampong Cham Communities, Cambodia, 2007-2009

Sopheak HemSowath Ly, Irene Votsi, Florian Vogt, Nima Asgari, Philippe BuchySeiha Heng, Mathieu Picardeau, Touch Sok, Sovann Ly, Rekol Huy, Bertrand Guillard, Simon Cauchemez, Arnaud Tarantola.

PLOS ONE. Public Library of Science; 2016;11(4):e0151555. DOI: 10.1371/journal.pone.0151555


Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia

Kim R. Blasdell*, Veasna Duong*, Marc Eloit, Fabrice Chretien, Sowath LyVibol HulVincent Deubel, Serge Morand, Philippe Buchy.

Elife. 2016;5. DOI: 10.7554/eLife.13135


Evidence of two distinct phylogenetic lineages of dog rabies virus circulating in Cambodia

Channa Mey*, Artem Metlin*, Veasna DuongSivuth OngSotheary InPaul F. Horwood, Jean-Marc Reynes, Hervé Bourhy, Arnaud TarantolaPhilippe Buchy.

Infection, Genetics and Evolution. 2016;38:55‑61. DOI: 10.1016/j.meegid.2015.12.011


Factors associated with the failure of first and second-line antiretroviral therapies therapy, a case control study in Cambodian HIV-1 infected children

Hubert Barennes, Kang Virak, François Rouet, Yves Buisson, Michel Strobel, Ung Vibol.

BMC Research Notes. 2016;9(1):69. DOI: 10.1186/s13104-016-1884-y


High Mortality Risk in Hypoglycemic and Dysglycemic Children Admitted at a Referral Hospital in a Non Malaria Tropical Setting of a Low Income Country

Hubert Barennes, Eng Sayavong, Eric Pussard.

PLOS ONE. Public Library of Science; 2016;11(2):e0150076. DOI: 10.1371/journal.pone.0150076


Intense circulation of A/H5N1 and other avian influenza viruses in Cambodian live-bird markets with serological evidence of sub-clinical human infections

Srey Viseth HormArnaud TarantolaSareth RithSowath LyJuliette GambarettiVeasna DuongPhalla Y, San Sorn, Davun Holl, Lotfi Allal, Wantanee Kalpravidh, Philippe DussartPaul F. HorwoodPhilippe Buchy.

Emerg Microbes Infect. 2016;5(7):e70. DOI: 10.1038/emi.2016.69


Intensive circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia

Julien CappelleVeasna Duong, Long Pring, Lida Kong, Maud Yakovleff, Didot Budi Prasetyo, Borin PengRithy ChoeungRaphaël DubozSivuth Ong, San Sorn, Philippe DussartArnaud Tarantola, Philippe Buchy, Véronique Chevalier.

PLoS Negl Trop Dis. 2016;10(12). DOI: 10.1371/journal.pntd.0005149


Laboratory diagnostics in dog-mediated rabies: an overview of performance and a proposed strategy for various settings

Veasna Duong*, Arnaud Tarantola*, Sivuth OngChanna MeyRithy ChoeungSowath Ly, Hervé Bourhy, Philippe Dussart**, Philippe Buchy**.

Int J Infect Dis. 2016;46:107‑14. DOI: 10.1016/j.ijid.2016.03.016


Long-Lasting Immune Protection and Other Epidemiological Findings after Chikungunya Emergence in a Cambodian Rural Community, April 2012

Beatriz Galatas*, Sowath Ly*, Veasna Duong, Kathy Baisley, Kunthy Nguon, Siam Chan, Rekol Huy, Sovann Ly, Sopheak Sorn, Leakhann Som, Philippe Buchy**, Arnaud Tarantola**.

PLoS Negl Trop Dis. Public Library of Science; 2016;10(1):e0004281. DOI: 10.1371/journal.pntd.0004281


Performance of Xpert MTB/RIF and Alternative Specimen Collection Methods for the Diagnosis of Tuberculosis in HIV-Infected Children

Olivier Marcy, Vibol Ung, Sophie Goyet, Laurence Borand, Philippe Msellati, Mathurin Tejiokem, Ngoc Lan Nguyen Thi, Boubacar Nacro, Sokleaph Cheng, Sara Eyangoh, Thu Hang Pham, Abdoul-Salam Ouedraogo, Arnaud Tarantola, Sylvain Godreuil, Stéphane Blanche, Christophe Delacourt, for the PAANTHER study group.

Clin Infect Dis. 2016;62(9):1161‑8. DOI: 10.1093/cid/ciw036


Rabies transmission risks during peripartum–Two cases and a review of the literature

Christiane Tshabu Aguèmon, Arnaud Tarantola*, Eugène Zoumènou, Sophie Goyet, Pamphile Assouto, Sowath Ly, Serge Mewanou, Hervé Bourhy, Betty Dodet, Abdou-Rahmann Aguèmon.

Vaccine. 2016;34(15):1752‑7. DOI: 10.1016/j.vaccine.2016.02.065


Seroepidemiology of Human Enterovirus 71 Infection among Children, Cambodia

Paul F. Horwood, Alessio Andronico, Arnaud Tarantola, Henrik Salje, Veasna Duong, Channa Mey, Sovann Ly, Philippe Dussart, Simon Cauchemez, Philippe Buchy.

Emerging Infectious Diseases journal – CDC. Volume 22, Number 1—January 2016.  DOI: 10.3201/eid2201.151323


First reported case of intraocular Gnathostoma spinigerum in Cambodia. Hem S, Tarantola A, Chheang R, Nop P, Kerléguer A.  Bull Soc Pathol Exot. 2015 Dec;108(5):312-5. doi: 10.1007/s13149-015-0453-2. Epub 2015 Sep 29.

An organizational analysis of road traffic crash prevention to explain the difficulties of a national program in a low income country. Vogel T, Reinharz D, Gripenberg M, Barennes H.  BMC Res Notes. 2015 Sep 28;8:486. doi: 10.1186/s13104-015-1472-6.

Evidence of High Out of Pocket Spending for HIV Care Leading to Catastrophic Expenditure for Affected Patients in Lao People’s Democratic Republic. Vogel T, Reinharz D, Gripenberg M, Barennes H. . BMC Res Notes. 2015 Sep 28;8:486. doi: 10.1186/s13104-015-1472-6.

Insect Consumption to Address Undernutrition, a National Survey on the Prevalence of Insect Consumption among Adults and Vendors in Laos. Barennes H, Frichittavong A, Gripenberg M, Koffi P.  PLoS One. 2015 Sep 1;10(9):e0136664. doi: 10.1371/journal.pone.0136664. eCollection 2015.

Bridge hosts, a missing link for disease ecology in multi-host systems. Caron A, Cappelle J, Cumming GS, de Garine-Wichatitsky M, Gaidet N. Vet Res. 2015 Jul 21;46:83. doi: 10.1186/s13567-015-0217-9.

Beriberi (thiamine deficiency) and high infant mortality in northern Laos. Barennes H, Sengkhamyong K, René JP, Phimmasane M.  PLoS Negl Trop Dis. 2015 Mar 17;9(3):e0003581. doi: 10.1371/journal.pntd.0003581. eCollection 2015.

How to reach the poor? Surveillance in low-income countries, lessons from experiences in Cambodia and Madagascar. Goutard FL, Binot A, Duboz R, Rasamoelina-Andriamanivo H, Pedrono M, Holl D, Peyre MI, Cappelle J, Chevalier V, Figuié M, Molia S, Roger FL. Prev Vet Med. 2015 Jun 1;120(1):12-26. doi: 10.1016/j.prevetmed.2015.02.014. Epub 2015 Feb 25.

Road traffic injuries in northern Laos: trends and risk factors of an underreported public health problem. Günther Slesa, Saythong Inthalath, Annelies Wilder-Smith and Hubert Barennes. Tropical Medicine and International Health, doi:10.1111/tmi.12562, John Wiley & Sons Ltd 2015.

Necrotic Tuberculin Skin (Mantoux) Test Reaction: A Case Report and an Estimation of Frequency. Bunnet D, Kerleguer A, Kim P, Pean P, Phuong V, Heng N, Peng Y, Borand L, Tarantola A. Chest 2015, 148(1):e1-4.

Rabies Vaccine and Rabies Immunoglobulin in Cambodia: Use and Obstacles to Use. Tarantola, A., S. Ly, S. In, S. Ong, Y. Peng, N. Heng and P. Buchy.  J Travel Med 22, no. 5 (2015): 348-52.

Low Frequency of Acute Hepatitis E Virus (Hev) Infections but High Past Hev Exposure in Subjects from Cambodia with Mild Liver Enzyme Elevations, Unexplained Fever or Immunodeficiency Due to Hiv-1 Infection. Nouhin J, Barennes H, Madec Y, Prak S, Hou SV, Kerleguer A, Kim S, Pean P, Rouet F.  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2015, 71:22-27.

Premier Cas De Gnathostomose Intra-Oculaire a Gnathostoma Spinigerum, Diagnostique Au Cambodge. Hem, S., A. Tarantola, R. Chheang, P. Nop and A. Kerleguer.  Bull Soc Pathol Exot 108, no. 5 (2015): 312-315.

Gaps between Research and Public Health Priorities in Low Income Countries: Evidence from a Systematic Literature Review Focused on Cambodia. Goyet, S., S. Touch, P. Ir, S. SamAn, T. Fassier, R. Frutos, A. Tarantola and H. Barennes.  Implement Sci 10,  (2015): 32.

Mortality in Cambodia: An 18-Month Prospective Community-Based Surveillance of All-Age Deaths Using Verbal Autopsies. Goyet, S., B. Rammaert, M. McCarron, V. Khieu, I. Fournier, P. Kitsutani, S. Ly, A. Mounts, W. G. Letson, P. Buchy and S. Vong.  Asia Pac J Public Health. 2015; 27(2): NP2458-70. doi: 10.1177/1010539513514433. Epub 2013 Dec 19.

Asymptomatic Humans Transmit Dengue Virus to Mosquitoes. Duong, V., L. Lambrechts, R. E. Paul, S. Ly, R. S. Lay, K. C. Long, R. Huy, A. Tarantola, T. W. Scott, A. Sakuntabhai and P. Buchy.  Proc Natl Acad Sci U S A 112, no. 47 (2015): 14688-93.

Value of Routine Dengue Diagnostic Tests in Urine and Saliva Specimens. Andries, A. C., V. Duong, S. Ly, J. Cappelle, K. S. Kim, P. Lorn Try, S. Ros, S. Ong, R. Huy, P. Horwood, M. Flamand, A. Sakuntabhai, A. Tarantola and P. Buchy. PLoS Negl Trop Dis 9, no. 9 (2015): e0004100.

Reasons for routine episiotomy: A mixed-methods study in a large maternity hospital in Phnom Penh, Cambodia. Clémence Schantz, Kruy Leang Sim, Ek Meng Ly, Hubert Barennes, So Sudaroth, Sophie Goyet. Published by Elsevier BV. Doi: 10.1016/j.rhm.2015.06.012. C Schantz et al. 2015

TB-IRIS, T-Cell Activation, and Remodeling of the T-Cell Compartment in Highly Immunosuppressed Hiv-Infected Patients with TB. Haridas, V., P. Pean, L. D. Jasenosky, Y. Madec, D. Laureillard, T. Sok, S. Sath, L. Borand, O. Marcy, S. Chan, E. Tsitsikov, J. F. Delfraissy, F. X. Blanc, A. E. Goldfeld and Capri- T. Study Team. AIDS. 2015 Jan 28;29(3):263-73. doi: 10.1097/QAD.0000000000000546.



TB-IRIS, T-Cell Activation, and Remodeling of the T-Cell Compartment in Highly Immunosuppressed Hiv-Infected Patients with TB. Rith S, Davis CT, Duong V, Sar B, Horm SV, Chin S, Ly S, Laurent D, Richner B, Oboho I, Jang Y, Davis W, Thor S, Balish A, Iuliano AD, Sorn S, Holl D, Sok T, Seng H, Tarantola A, Tsuyuoka R, Parry A, Chea N, Allal L, Kitsutani P, Warren D, Prouty M, Horwood P, Widdowson MA, Lindstrom S, Villanueva J, Donis R, Cox N, Buchy P. J Virol. 2014 Dec;88(23):13897-909. doi: 10.1128/JVI.01887-14.

Perceived stigma by children on antiretroviral treatment in Cambodia. Barennes H, Tat S, Reinharz D, Vibol U. Perceived stigma by children on antiretroviral treatment in Cambodia. BMC Pediatr. 2014 Dec 10;14(1):300.

Improving the Management of Dysglycemia in Children in the Developing World. Barennes H, Pussard E. Improving the Management of Dysglycemia in Children in the Developing World. Am J Trop Med Hyg. 2014 Oct 13.

Virological failure and HIV-1 drug resistance mutations among naive and antiretroviral pre-treated patients entering the ESTHER program of Calmette Hospital in Cambodia. Barennes H, Guillet S, Limsreng S, Him S, Nouhin J, Hak C, Srun C, Viretto G, Ouk V, Delfraissy JF, Ségéral O. PLoS One. 2014 Aug 28;9(8):e105736. doi: 10.1371/journal.pone.0105736. eCollection 2014.

Causes and determinants of mortality in HIV-infected adults with tuberculosis: an analysis from the CAMELIA ANRS 1295-CIPRA KH001 randomized trial. Marcy O, Laureillard D, Madec Y, Chan S, Mayaud C, Borand L, Prak N, Kim C,Lak KK, Hak C, Dim B, Sok T, Delfraissy JF, Goldfeld AE, Blanc FX; CAMELIA (ANRS 1295-CIPRA KH001) Study Team. Causes and determinants of mortality in HIV-infected adults with tuberculosis: an analysis from the CAMELIA ANRS 1295-CIPRA KH001 randomized trial. Clin Infect Dis. 2014 Aug;59(3):435-45.

Knowledge translation: a case study on pneumonia research and clinical guidelines in a low- income country. Goyet S, Barennes H, Libourel T, van Griensven J, Frutos R, Tarantola A. Implement Sci. 2014 Jun 26;9:82.

Two clustered cases of confirmed influenza A(H5N1) virus infection, Cambodia, 2011. Chea N, Yi SD, Rith S, Seng H, Ieng V, Penh C, Mardy S, Laurent D, Richner B, Sok T, Ly S, Kitsutani P, Asgari N, Roces MC, Buchy P, Tarantola A. Euro Surveill. 2014 Jun 26;19(25). pii: 20839.

Fluoroquinolone resistance and Mycobacterium tuberculosis: CAP guidelines play an important role. Goyet S, Vlieghe E, Lim K, van Griensven J, Borand L, Thong P, Rammaert B, Marcy O, Tarantola A.  Int J Tuberc Lung Dis. 2014 May;18(5):628-30.

Etiologies and Resistance Profiles of Bacterial Community-Acquired Pneumonia in Cambodian and Neighboring Countries’ Health Care Settings: A Systematic Review (1995 to 2012). Goyet S, Vlieghe E, Kumar V, Newell S, Moore CE, Bousfield R, Leang HC, Chuop S, Thong P, Rammaert B, Hem S, van Griensven J, Rachmat B, Fassier T, Lim K, Tarantola A. PLoS One. 2014 Mar 13;9(3):e89637

Plasma concentrations, efficacy and safety of efavirenz in HIV-infected adults treated for tuberculosis in Cambodia (ANRS 1295-CIPRA KH001 CAMELIA trial). Borand L, Madec Y, Laureillard D, Chou M, Marcy O, Pheng P, Prak N, Kim C, Lak KK, Hak C, Dim B, Nerrienet E, Fontanet A, Sok T, Goldfeld AE, Blanc FX, Taburet AM. PLoS One. 2014 Mar 7;9(3):e90350.

Risk factors for hepatitis C transmission in HIV patients, Hepacam study, ANRS 12267 Cambodia. Goyet S, Lerolle N, Fournier-Nicolle I, Ken S, Nouhin J, Sowath L, Barennes H, Hak C, Ung C, Viretto G, Delfraissy JF, Khuon P, Segeral O.  AIDS Behav. 2014 Mar;18(3):495-504. doi: 10.1007/s10461-013-0486-0.

Spatial epidemiology and climatic predictors of paediatric dengue infections captured via sentinel site surveillance, Phnom Penh Cambodia 2011-2012. Lover AA, Buchy P, Rachline A, Moniboth D, Huy R, Meng CY, Leo YS, Yuvatha K, Sophal U, Chantha N, Y B, Duong V, Goyet S, Brett JL, Tarantola A, Cavailler P. BMC Public Health. 2014; 14:658. doi: 10.1186/1471-2458-14-658.

Epidemiological and virological characteristics of influenza viruses circulating in Cambodia from 2009 to 2011. Horm SV, Mardy S, Rith S, Ly S, Heng S, Vong S, Kitsutani P, Ieng V, Tarantola A, Ly S, Sar B, Chea N, Sokhal B, Barr I, Kelso A, Horwood PF, Timmermans A, Hurt A, Lon C, Saunders D, Ung SA, Asgari N, Roces MC, Touch S, Komadina N, Buchy P. PLoS One. 2014; 9(10):e110713. doi: 10.1371/journal.pone.0110713.

Epidemiological analysis of influenza A infection in Cambodian pigs and recommendations for surveillance strategies. Netrabukkana P, Cappelle J, Trevennec C, Roger F, Goutard F, Buchy P, Robertson I, Fenwick S. Transbound Emerg Dis. 2014; doi: 10.111/tbed.12204.

A rapid assessment of flying fox (Pteropus spp.) colonies in Cambodia. Ravon S., Furey N., Hul V and Cappelle J. A rapid assessment of flying fox (Pteropus spp.) colonies in Cambodia. Cambodian Journal of Natural History 2014 (1) 14–18

Melioidosis Requires Better Data Sharing for Improved Diagnosis and Management in the Mekong Region. Rammaert B; Goyet S; Tarantola A. Melioidosis Requires Better Data Sharing for Improved Diagnosis and Management in the Mekong Region. Am. J. Trop. Med. Hyg., 90(2), 2014, p. 383.

Risks of avian influenza transmission in areas of intensive free-ranging duck production with wild waterfowl. Cappelle J, Zhao D, Gilbert M, Nelson MI, Newman SH, Takekawa JY, Gaidet N, Prosser DJ, Liu Y, Li P, Shu Y, Xiao X. Risks of avian influenza transmission in areas of intensive free-ranging duck production with wild waterfowl. Ecohealth. 2014;11(1):109-19.

Dependence of efavirenz-and rifampicin-isoniazid-based antituberculosis treatment drug-drug interaction on CYP2B6 and NAT2 genetic polymorphisms: ANRS 12154 study in Cambodia. Bertrand J, Verstuyft C, Chou M, Borand L, Chea P, Nay KH, Blanc FX, Mentré F, Taburet AM; CAMELIA (ANRS 1295-CIPRA KH001) Study Group.  J Infect Dis. 2014 Feb 1;209(3):399-408

Paragonimiasis as an important alternative misdiagnosed disease for suspected acid-fast bacilli sputum smear-negative tuberculosis. Barennes H, Slesak G, Buisson Y, Odermatt P.  Am J Trop Med Hyg. 2014 Feb;90(2):384-5.

Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the mekong region. Tarantola A, Goutard F, Newton P, de Lamballerie X, Lortholary O, Cappelle J, Buchy P. PLoS Negl Trop Dis. 2014 Jan 30;8(1):e2533. doi: 10.1371/journal.pntd.0002533.

Randomised pharmacokinetic trial of rifabutin with lopinavir/ritonavir-antiretroviral therapy in patients with HIV-associated tuberculosis in Vietnam. Lan NT, Thu NT, Barrail-Tran A, Duc NH, Lan NN, Laureillard D, Lien TT, Borand L, Quillet C, Connolly C, Lagarde D, Pym A, Lienhardt C, Dung NH, Taburet AM, Harries AD. Randomised pharmacokinetic trial of rifabutin with lopinavir/ritonavir-antiretroviral therapy in patients with HIV-associated tuberculosis in Vietnam. PLoS One. 2014 Jan 22;9(1):e84866.

A study of the genetic variability of human respiratory syncytial virus (HRSV) in Cambodia reveals the existence of a new HRSV group B genotype. Arnott A, Vong S, Mardy S, Chu S, Naughtin M, Sovann L, Buecher C, Beauté J, Rith S, Borand L, Asgari N, Frutos R, Guillard B, Touch S, Deubel V, Buchy P. J ClinMicrobiol. 2011 Oct;49(10):3504-13. doi: 10.1128/JCM.01131-11. Epub 2011 Aug 24.


Cluster randomised trial of the impact of biosecurity measures on poultry health in backyard flocks.Conan A, Goutard FL, Holl D, Ra S, Ponsich A, Tarantola A, Sorn S, Vong S. Vet J. 2013 Dec;198(3):649-55.

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome after early initiation of antiretroviral therapy in a randomized clinical trial. Laureillard D, Marcy O, Madec Y, Chea S, Chan S, Borand L, Fernandez M, Prak N, Kim C, Dim B, Nerrienet E, Sok T, Delfraissy JF, Goldfeld AE, Blanc FX; CAMELIA (ANRS 1295 – CIPRA KH001) Study Team. P.  AIDS. 2013 Oct 23;27(16):2577-86.

Unusual increase in reported cases of paratyphoid A fever among travellers returning from Cambodia, January to September 2013. Tourdjman M, Le Hello S, Gossner C, Delmas G, Tubiana S, Fabre L, Kerléguer A, Tarantola A, Fruth A, Friesema I, Thorstensen Brandal L, Lawrence J, Fisher I, Dufour M, Weill FX, de Valk H. 

Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country. Rammaert B, Goyet S, Tarantola A, Hem S, Rith S, Cheng S, Te V, Try PL, Guillard B, Vong S, Mayaud C, Buchy P, Borand L.  Respir Med. 2013 Oct;107(10):1625-32. doi: 10.1016/j.rmed.2013.07.018. Epub 2013 Aug 9.

The ethics of a clinical trial when the protocol clashes with international guidelines. N. T. N. Lan, N. T. N. Thu, N. H. Duc, N. N. Lan, T. T. X. Lien, N. H. Dung, A-M. Taburet, D. Laureillard, L. Borand, C. Quillet, D. Lagarde, A. Pym, C. Connolly, C. Lienhardt, C. Rekacewicz, A. D. Harries. Public Health Action, Volume 3, Number 2, 21 June 2013, pp. 97-102(6).

Risk Factors for Hepatitis C Transmission in HIV Patients, Hepacam Study, ANRS 12267 Cambodia. Goyet S, Lerolle N, Fournier-Nicolle I, Ken S, Nouhin J, Sowath L, Barennes H, Hak C, Ung C, Viretto G, Delfraissy JF, Khuon P, Segeral O. AIDS Behav. 2014 Mar;18(3):495-504. doi: 10.1007/s10461-013-0486-0.

Use of a text message-based pharmacovigilance tool in Cambodia: pilot study. Baron S, Goutard F, Nguon K, Tarantola A.  J Med Internet Res. 2013 Apr 16;15(4):e68

Development of a checklist of quality indicators for clinical trials in resource-limited countries: The French National Agency for Research on AIDS and viral hepatitis (ANRS) experience. Hanna M, Minga A, Fao P, Borand L, Diouf A, Mben J-M, Gad R, Anglaret X, Bazin B, Chene G, and the [Quali-PED] ANRS 12175 study group.  Clin Trials. 2013 Apr;10(2):300-18

Human bocavirus (HBoV) amongst an all-ages population hospitalized with acute lower respiratory infections in Cambodia. Influenza and Other Respiratory Viruses. Arnott A, Vong S, Rith S, Naughtin M, Ly S, Guillard B, Deubel V, Buchy P. 2013 Mar; 7(2): 201-10. doi: 10.1111/j.1750-2659.2012.00369.x.


Acute lower respiratory infections in >=5 year-old hospitalized patients in Cambodia, a low-income tropical country: clinical characteristics and pathogenic etiology.  Vong S, Guillard B, Borand L, Rammaert B, Goyet S, Te V, Lorn Try P, Hem S, Rith S, Ly S, Cavailler P, Mayaud C, Buchy P. BMC Infect Dis. 2013 Feb 22; 13(1): 97.

Tuberculosis and HIV co-infection: clinical trial under the coordination of the Institut Pasteur in Cambodia. Borand L, Pheng P, Saman M, Leng C, Chea P, Sarady Ay S, Suom S, Roat Men N, Nerrienet E, Marcy O.  Med Sci (Paris) 2013;29:908-11. Review. French.

Complex dynamic of dengue virus serotypes 2 and 3 in Cambodia following series of climate disasters. Duong V, Henn MR, Simmons C, Ngan C, Y B, Gavotte L, Viari A, Ong S, Huy R, Lennon NJ, Ly S, Vong S, Birren BW, Farrar JJ, Deubel V, Frutos R, Buchy P. Infect Genet Evol. 2013; 15:77-86. doi: 10.1016/j.meegid.2012.05.012.

Genetic variability of human metapneumovirus amongst an all ages population in Cambodia between 2007 and 2009.  Arnott A, Vong S, Sek M, Naughtin M, Beauté J, Rith S, Guillard B, Deubel V, Buchy P.  Infect Genet Evol. 2013 Apr;15:43-52. doi: 10.1016/j.meegid.2011.01.016. Epub 2011 Feb 1.


Serologic evidence of human influenza virus infections in swine populations, Cambodia. Rith S, Netrabukkana P, Sorn S, Mumford E, Mey C, Holl D, Goutard F, Y B, Fenwick S, Robertson I, Roger F, Buchy P. Serologic evidence of human influenza virus infections in swine populations, Cambodia. Influenza Other Respi Viruses 2013; 7(3): 271-9. doi: 10.1111/j.1750-2659.2012.00382.

Only a sixth of animal bite victims in India get antirabies treatment. Tarantola A, Ly S, In S, Deubel V, Buchy P. BMJ. 2013 Oct 7;347:f6040. doi: 10.1136/bmj.f6040.

Acute viral lower respiratory tract infections in cambodian children: clinical and epidemiologic characteristics. Guerrier G, Goyet S, Chheng ET, Rammaert B, Borand L, Te V, Try PL, Sareth R, Cavailler P, Mayaud C, Guillard B, Vong S, Buchy P, Tarantola A. Pediatr Infect Dis J. 2013 Jan;32(1):e8-e13.


A Community-based Education Trial to Improve Backyard Poultry Biosecurity in Rural Cambodia. Conan A, Ponsich A, Luce Goutard F, Khiev R, Tarantola A, Sorn S, Vong S. Acta Trop. 2012 Dec 19;125(3):294-302.

Plasma concentrations of efavirenz with a 600 mg standard dose in Cambodian HIV-infected adults treated for tuberculosis with a body weight above 50 kg. Borand L, Laureillard D, Madec Y, Chou M, Pheng P, Marcy O, Sok T, Goldfeld AE, Taburet AM, Blanc FX; the CAMELIA (ANRS 1295-CIPRA KH001) study team.  Antivir Ther. 2013;18(3):419-23. doi: 10.3851/IMP2483. Epub 2012 Dec 12.

Biosecurity measures for backyard poultry in developing countries: a systematic review. Conan A, Goutard FL, Sorn S, Vong S. Biosecurity measures for backyard poultry in developing countries: a systematic review. BMC Vet Res. 2012 Dec 7;8(1):240

Reemergence of Chikungunya virus in Cambodia. Duong V, Andries AC, Ngan C, Sok T, Richner B, Asgari-Jirhandeh N, Bjorge S, Huy R, Ly S, Laurent D, Hok B, Roces MC, Ong S, Char MC, Deubel V, Tarantola A, Buchy P. Emerg Infect Dis. 2012 Dec;18(12):2066-9.

Can human movements explain heterogeneous propagation of dengue Fever in Cambodia? Teurlai M, Huy R, Cazelles B, Duboz R, Baehr C, Vong S. Can human movements explain heterogeneous propagation of dengue Fever in Cambodia? PLoS Negl Trop Dis. 2012 Dec;6(12):e1957.

Chikungunya Outbreak — Cambodia, February–March 2012. Sowath Ly, PhD, Sopheak Sorn, MA, Arnaud Tarantola, MD, Epidemiology and Public Health Unit; Lydie Canier, MSc, Molecular Epidemiology and Malariology Unit; Philippe Buchy, PhD, Veasna Duong, PhD, Virology Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia. Ilin Chuang, MD, Steven Newell, PhD, U.S. Naval Medical Research Unit 2, Phnom Penh, Cambodia. Sovann Ly, MD, Touch Sok, MD, Vandy Som, MD, Communicable Disease Control Dept; Meng Chuor Char, MD, Chantha Ngan, MD, National Center for Malaria Control, Parasitology and Entomology, Ministry of Health of Cambodia. Leakhann Som, MD, Kampong Speu Provincial Health Dept, Kampong Speu, Cambodia. Maria Concepcion Roces, MD, World Health Organization, Phnom Penh, Cambodia. September 21, 2012 / 61(37);737-740.

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study. Dawood FS, Iuliano AD, Reed C, Meltzer MI, Shay DK, Cheng PY, Bandaranayake D, Breiman RF, Brooks WA, Buchy P, Feikin DR, Fowler KB, Gordon A, Hien NT, Horby P, Huang QS, Katz MA, Krishnan A, Lal R, Montgomery JM, Mølbak K, Pebody R, Presanis AM, Razuri H, Steens A, Tinoco YO, Wallinga J, Yu H, Vong S, Bresee J, Widdowson MA.  Lancet Infect Dis. 2012 Sep;12(9):687-95. Erratum in: Lancet Infect Dis. 2012 Sep;12(9):655.

Identifying live bird markets with the potential to act as reservoirs of avian influenza A (H5N1) virus: a survey in northern Viet Nam and Cambodia. Fournié G, Guitian J, Desvaux S, Mangtani P, Ly S, Cong VC, San S, Dung do H, Holl D, Pfeiffer DU, Vong S, Ghani AC. Identifying live bird markets with the potential to act as reservoirs of avian influenza A (H5N1) virus: a survey in northern Viet Nam and Cambodia. PLoS One. 2012;7(6):e37986. doi:10.1371/journal.pone.0037986. Epub 2012 Jun 4.

Natural killer cell degranulation capacity predicts early onset of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients with tuberculosis. Pean P, Nerrienet E, Madec Y, Borand L, Laureillard D, Fernandez M, Marcy O, Sarin C, Phon K, Taylor S, Pancino G, Barré-Sinoussi F, Scott-Algara D; Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team.  Blood. 2012 Apr 5;119(14):3315-20.

Under-recognition and reporting of dengue in Cambodia: a capture-recapture analysis of the National Dengue Surveillance System. Vong S, Goyet S, Ly S, Ngan C, Huy R, Duong V, Wichmann O, Letson GW, Margolis HS, Buchy P.  Epidemiol Infect. 2012 Mar;140(3):491-9. doi: 10.1017/S0950268811001191. Epub 2011 Jun 21.

Anthropology and Clinical Trial Emerging Reproductive Issues in Cambodia. Hancart Petitet Pascale. Anthropology and Clinical Trial Emerging Reproductive Issues in Cambodia. International Journal of Social Science and Humanity. 2012; 2 (2): 139-142.

Clinical and virological study of dengue cases and the members of their households: the multinational DENFRAME Project. Dussart P, Baril L, Petit L, Beniquel L, Quang LC, Ly S, Azevedo Rdo S, Meynard JB, Vong S, Chartier L, Diop A, Sivuth O, Duong V, Thang CM, Jacobs M, Sakuntabhai A, Nunes MR, Huong VT, Buchy P, Vasconcelos PF. PLoS Negl Trop Dis. 2012 Jan;6(1):e1482.

Klebsiella pneumoniae related community-acquired acute lower respiratory infections in Cambodia: clinical characteristics and treatment. Rammaert B, Goyet S, Beauté J, Hem S, Te V, Try PL, Mayaud C, Borand L, Buchy P, Guillard B, Vong S.  BMC Infect Dis. 2012 Jan 10;12:3.

Expansion of European vacA and cagA alleles to East-Asian Helicobacter pylori strains in Cambodia. Breurec S, Guillard B, Hem S, Papadakos KS, Brisse S, Huerre M et al. Expansion of European vacA and cagA alleles to East-Asian Helicobacter pylori strains in Cambodia. Infect Genet Evol. 2011 Dec;11(8):1899-905.

Clinical and virological factors influencing the performance of a NS1 antigen-capture assay and potential use as a marker of dengue disease severity. Duong V, Ly S, Lorn Try P, Tuiskunen A, Ong S, Chroeung N, Lundkvist A, Leparc-Goffart I, Deubel V, Vong S, Buchy P.  PLoSNegl Trop Dis. 2011 Jul;5(7):e1244. doi: 10.1371/journal.pntd.0001244. Epub 2011 Jul 19.

Factors associated with negative direct sputum examination in Asian and African HIV-infected patients with tuberculosis (ANRS 1260). Chartier L, Leng C, Sire JM, Le Minor O, Saman M, Bercion R  et al. Factors associated with negative direct sputum examination in Asian and African HIV-infected patients with tuberculosis (ANRS 1260). PLoS One. 2011;6(6):e21212. Epub 2011 Jun 23

Pulmonary melioidosis in Cambodia: a prospective study. Rammaert B, Beauté J, Borand L, Hem S, Buchy P, Goyet S, Overtoom R, Angebault C, Te V, Try PL, Mayaud C, Vong S, Guillard B.  BMC Infect Dis. 2011 May 14;11:126. doi: 10.1186/1471-2334-11-126.

Une approche socioculturelle de l’hygiène au Cambodge. Pratiques soignantes et risques de transmission virale. P. Hancart-Petitet, C. Dumas, A.-L. Faurand-Tournaire, S. Vong, A. Desclaux. Une approche socioculturelle de l’hygiène au Cambodge. Pratiques soignantes et risques de transmission virale. Hygiènes – XIX – n°2 Avril 2011

Social and cultural dimensions of hygiene in Cambodian health care facilities. Hancart-Petitet P, Dumas C, Faurand-Tournaire AL, Desclaux A, Vong S. Social and cultural dimensions of hygiene in Cambodian health care facilities. BMC Public Health. 2011 Feb 7;11:83.

Population Pharmacokinetics of Nevirapine in HIV-1 infected Pregnant Women and their neonates (ANRS 12109). S. Benaboud, D. Ekouévi, S. Urien, E. Rey, E. Arrivé, S. Blanche, G. Gray, K. Sim, D. Avit, J. McIntyre, E. Nerrienet, F. Dabis, J-M. Tréluyer, D. Hirt and the TEmAA ANRS12109 Study Group. Population Pharmacokinetics of Nevirapine in HIV-1 infected Pregnant Women and their neonates (ANRS 12109). Antimicrobial Agents and Chemotherapy 2011 Jan;55(1):331-7.